Irinotecan-induced Non-alcoholic Steatohepatitis: The Role of Gut Bacterial Translocation

Abstract

secondary endpoints are predicting factors for tumor recurrence and MJR. Results: Among the 121 TACE patients, 106 (87.6%) could be measured PR. The mean interval between TACE and hepatic resection was 33.1 days. 5 year DFS rates by PR status were as follows: 40.6% CPR, 43.7% MJR, and 49.0% MNR. There was also no significant difference in overall survival between 3 groups. Multivariate analyses revealed that microvascular invasion and capsular invasion (P = 0.001, hazard ratio [HR]: 13.7 and P = 0.031, HR: 2.3) were independent predictors for DFS. Multivariate analysis of the predictors of > 50% PR revealed that hepatitis B antigen positive and capsular invasion were independent factors. Conclusions: These data could reflect the PR after TACE for resectable HCC may not be useful for predicting recurrence of HCC after resection.