Iridoids modulate inflammation in diabetic kidney disease: A review

Zhou, Tong-yi; Tian, Na; Li, Liu; Yu, Rong

doi:10.1016/j.joim.2024.03.010

Journal of Integrative Medicine

2024

DOI: 10.1016/j.joim.2024.03.010

|View full text |Cite

Iridoids modulate inflammation in diabetic kidney disease: A review

Tong-yi Zhou,

Na Tian,

Liu Li

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 161 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Novel Iridoid Derivatives Isolated from the Roots of Patrinia scabra with Potential Anti-Renal Fibrosis Activity In Vitro

Li,

Xu,

Sun

et al. 2024

Molecules

View full text Add to dashboard Cite

Scabrol B and Scabrol C, two newly identified iridoid derivatives (1 and 2) and six known compounds (3–8), were extracted from the roots of Patrinia scabra. The structures of these derivatives, including their absolute configurations, were elucidated via comprehensive NMR analysis, chemical derivatization, and quantum chemical ECD calculations. All isolated compounds were evaluated for their anti-renal fibrosis activity. The results demonstrate that compounds 1 and 2 showed dose-dependent protective effects against renal fibrosis in vitro by reducing the expression of fibronectin, collagen I, and alpha-smooth muscle actin (α-SMA) in NRK-49f cells mediated by TGF-β1.

show abstract

Novel Iridoid Derivatives Isolated from the Roots of Patrinia scabra with Potential Anti-Renal Fibrosis Activity In Vitro

Li,

Xu,

Sun

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Iridoids modulate inflammation in diabetic kidney disease: A review

Cited by 1 publication

References 161 publications

Novel Iridoid Derivatives Isolated from the Roots of Patrinia scabra with Potential Anti-Renal Fibrosis Activity In Vitro

Novel Iridoid Derivatives Isolated from the Roots of Patrinia scabra with Potential Anti-Renal Fibrosis Activity In Vitro

Contact Info

Product

Resources

About