Iridocorneo-endotheliales Syndrom (ICE-S): Klassifikation, Klinik und Diagnostik

Herde, J.

doi:10.1055/s-2005-858119

Cited by 8 publications

(2 citation statements)

References 11 publications

(16 reference statements)

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“…However, secondary glaucoma does not correlate with the degree of synechial angle closure [23]. Obstruction of aqueous drainage is caused by either covering of the trabecular meshwork with membrane or synechial closure of iridocorneal angle [24,25].…”

Section: Discussionmentioning

confidence: 99%

The frequency of secondary glaucoma in patients with iridocorneal endothelial syndrome in correlation to the presence of uveal ectropion

et al. 2017

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Introduction/Objective Iridocorneal endothelial (ICE) syndrome incudes 3 clinical forms: progressive iris atrophy, Chandler's syndrome, and Cogan-Reese syndrome. It is characterized by various degrees of iris atrophy, corneal endothelial changes, uveal ectropion, corectopia, peripheral anterior synechiae (PAS) and secondary glaucoma. The aim of the study was to illustrate forms of ICE syndrome, determine frequency of secondary glaucoma with emphasis on cases with uveal ectropion, analyze response to medicament treatment and the need for surgical treatment in intraocular pressure (IOP) control. Methods Patients underwent slit lamp examination, applanation tonometry, gonioscopy, ophthalmoscopy, Humphrey visual field testing and Heidelberg retina tomography. Patients were divided into two groups: group I, without uveal ectropion (22 patients) and group II, with uveal ectropion (14 patients). Results A total of 36 patients were examined in a 10-year period. The average age was 38 years, male to female ratio 1:2. Secondary glaucoma was confirmed in 26 (72.2%) patients, out of which 12 (54.5%) in group I and 14 (100%) in group II. PAS were more frequent in group II. In group I, mean initial IOP was 37 mmHg, and after medicament treatment 26 mmHg. Secondary glaucoma was controlled in 50% and remaining 50% underwent surgical treatment. In group II, mean initial IOP was 49 mmHg, and after medicament treatment 32 mmHg. All 14 patients (100%) underwent surgical treatment in order to achieve IOP control. Conclusion ICE syndrome is a rare, progressive disease, with high incidence of secondary glaucoma, which is more frequent in cases with uveal ectropion. In these cases, medicament treatment is not effective and trabeculectomy with antimetabolite application is necessary.

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Section: Discussionmentioning

confidence: 99%

The frequency of secondary glaucoma in patients with iridocorneal endothelial syndrome in correlation to the presence of uveal ectropion

et al. 2017

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“…• zespół Chandlera, w którym dominują objawy rogówkowe jak obrzęk i związane z tym obniżenie ostrości wzroku, ciśnienie wewnątrzgałkowe jest zazwyczaj w normie, a atrofia tęczówki raczej łagodna [12] i rzadko kiedy prowadzi do otworów pełnej grubości [13]; • zespół Cogana-Reese'a, zwany również zespołem znamion tęczówki, charakteryzuje się mnogimi guzkami tęczów-ki, które mogą być uszypułowane, otoczonymi zanikiem krypt [13]; • postępujący zanik tęczówki cechujący się przemieszczeniem źrenicy (corectopia) i dodatkowymi pseudoźrenicami (pseudopolycoria) wynikający ze ścieńczenia tęczówki oraz z napięć, jakie wywołują obkurczająca się błona i obwodowe zrosty przednie [14]. Wyżej wymienione jednostki mogą się nakładać [15][16][17] i czasami zaszeregowanie do konkretnego zespołu może być problematyczne.…”

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