Iridium solvent complex as a new sensitive probe to detect benzimidazole pesticides based on photoluminescent signals “switch-on” via coordination mechanism

Novel Electrochemiluminescent Biosensor to Ultrasensitively Detect U94 Gene in Human Herpesvirus 6 Using Metal–Organic Framework-Based Nanoemitters Comprising Iridium(III) Complexes via One-Pot Coordination Reaction Strategy

“…As a branch of cyclometalated iridium­(III) complexes, the iridium­(III) solvent complex initially reported by Ma et al in 2008 is one kind of nonemissive iridium complex with weak coordination solvent ligands . Based on the coordination substituting reaction between the solvent ligands of nonemissive iridium­(III) solvent complex and analytes with imidazole unit to in situ generate new strong emissive iridium­(III) complex, iridium­(III) solvent complex has been developed as one kind of important phosphorescent switch-on probes in many analytical fields, such as proteins staining, imaging nuclei of living cells, peptides/antibody labeling, discrimination of bases in oligonucleotides, and monitoring histidine and benzimidazole pesticides . This has provided entirely fresh insights and a robust research foundation for the synthesis of novel luminescent materials.…”

“…It is well known that zeolitic imidazolate framework-8 (ZIF-8) is a typical type of MOF material composed of zinc ions and 2-methylimidazole ligands that are connected through coordination reactions to form a crystalline structure. Due to its mild synthesis conditions, high chemical/hydrothermal stabilities, large specific surface area, and high porosity, ZIF-8 has been widely used in wastewater treatment, energy chemistry, , catalysis, and analytical applications. ,, Considering the aforementioned results that the imidazole-skeleton ligand can bind with iridium­(III) solvent complexes to in situ form new intensive iridium­(III)-based luminophores under mild conditions, − it encourages us to generate iridium­(III)-based emission centers by doping iridium­(III) solvent complexes during the in situ synthesis of ZIF-8. Subsequently, these centers are encapsulated within the ZIF-8 framework, resulting in MOF-based ECL nanoemitters.…”