Iridium(iii)-catalyzed two-fold C–H alkylation of BINOLs with allyl alcohols

Abstract

Ir(III)-catalyzed C−H alkylation of BINOL units has been well examined by allyl alcohols as coupling partners. Under the advantage of pyridine guiding group, the efficient protocol allows the rapid synthesis...

Rhodium-Catalyzed Alkylation of Aromatic Ketones with Allylic Alcohols and α,β-Unsaturated Ketones

“…Allylic alcohols have the advantages of commercial availability, low cost, and easy preparation. The tandem reactions of C-H bond addition to allylic alcohol, β-hydride elimination, and keto-enol tautomerism generate β-aryl carbonyl compounds [7][8][9], which is identical with the direct addition of C-H bonds to α,β-unsaturated ketones. Therefore, allylic alcohols have been used as substitutes for α,β-unsaturated ketones in some cases.…”

Rhodium(iii)-catalyzed C–H alkylation of arylhydrophthalazinediones with α-Cl ketones as sp3-carbon alkylated agents

“…1 The intrinsic lipophilic character of an alkyl chain provides the desired characteristic features for agrochemicals and drugs. 2 Thus, the direct C–H alkylation, representing a significant transformation in molecular science, using directing groups has gained much attention in organic synthesis. 3…”