IRF4 suppresses osteogenic differentiation of BM-MSCs by transcriptionally activating miR-636/DOCK9 axis

miR-30a inhibits the osteogenic differentiation of the tibia-derived MSCs in congenital pseudarthrosis via targeting HOXD8

“…For instance, blocking the NLRP3 inflammasome could reduce osteogenic differentiation via inhibition of RUNX2 [ 33 ]. IRF4 could suppress osteogenic differentiation of BM-MSCs by inactivating RUNX2 [ 34 ]. CircRNA-23525 modulated RUNX2 expression by targeting miR-30a-3p, leading to positive regulation in the osteoblastic differentiation of adipose-derived mesenchymal stem cells (ADSCs) [ 16 ].…”