Irbesartan Substitution for Valsartan or Losartan in Treating Hypertension

Abstract

Irbesartan is an appropriate substitution for valsartan or losartan.

Successful Implementation of a P&T-Approved Therapeutic Interchange Program of Angiotensin II Receptor Blockers in a Medical Center in Taiwan

“…The study findings were in accord with results from other Western studies relating to similar ARB therapeutic interchange programs [24,25]. The results indicated that therapy conversion did not significantly affect blood pressure control among outpatients.…”

“…Although other therapeutic interchange programs involving ARBs have been described in Western countries, the concept is still controversial and has not yet been widely adopted in Taiwan and in other Asian countries [24,25]. The results proved that ARB therapeutic interchange can be effectively implemented for cost-savings purpose without compromising efficacy or increasing toxicity in this setting.…”

Impact of non-medical switching on clinical and economic outcomes, resource utilization and medication-taking behavior: a systematic literature review

“…Frequently, non-medical switching occurs as a result of formulary changes implemented in an attempt to reduce specific prescription drug costs [3][4][5][6][7][8][9][10][11] . While non-medical switching can decrease target drug acquisition costs, it may have unintended consequences for clinical and economic outcomes, overall healthcare resource utilization and patient medication-taking behaviors 12,13 .…”