Ir(tri-N-heterocyclic carbene)-catalyzed upgrading of glycerol: C–C bond formation for the synthesis of α-hydroxy acids

Abstract

Ir(triNHC) complexes catalyzed glycerol and alcohol dehydrogenative coupling, yielding diverse α-hydroxy acids. Unlike conventional conditions, Ir(triNHC) facilitated additional C-C bond formation after lactic acid production from glycerol, exhibiting high TOFs....