Ir nanoparticles with multi-enzyme activities and its application in the selective oxidation of aromatic alcohols

Jin, Guangxia; Liu, Jie; Wang, Chan; Gu, Wenxing; Ran, Guoxia; Liu, Bing; Song, Qijun

doi:10.1016/j.apcatb.2020.118725

Cited by 47 publications

(39 citation statements)

References 43 publications

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“…The existence of • OH was also investigated using TA as an indicator with light on and off. It was reported that TA exhibits an emission wavelength of 425 nm in the presence of • OH . As illustrated in Figure S5, no noticeable response was observed at 425 nm in the presence of AuRu NPs in the dark and upon irradiation, indicating that no • OH existed in the system.…”

Section: Resultssupporting

confidence: 70%

“…It was reported that TA exhibits an emission wavelength of 425 nm in the presence of • OH. 23 As illustrated in Figure S5, no noticeable response was observed at 425 nm in the presence of AuRu NPs in the dark and upon irradiation, indicating that no • OH existed in the system. The generation of reactive oxygen species (ROS) was further examined by ESR spectroscopy The large amounts of holes produced by AuRu NPs under illumination can promote the oxidation of AuRu NPs themselves in the absence of substrates, whereas the holes can be utilized for the electrocatalytic oxidization of glucose.…”

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confidence: 93%

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Plasmon-Enhanced Electroactivity of AuRu Nanostructures for Electroanalysis Applications

et al. 2021

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An electrochemical sensing interface is limited by poor reproducibility and inevitable interferences present in practical applications due to the weak electrochemical signals of nanotags. This motivates the need for effective strategies to enhance the electroactivity performances of nanotags. In this contribution, a plasmon-enhanced electroactivity mechanism is proposed for AuRu-based nanostructures under illumination and applied for accurate detection of human epidermal growth factor receptor-2 (HER2). AuRu nanoparticles (NPs) harvested light energy through plasmon excitation and generated holes to participate in the electrooxidation process. The production of holes resulted in the electrooxidation signal enhancement of AuRu NPs. AuRu NPs were assembled with Au NPs using HER2 aptamers as linkers, and the plasmonic coupling between AuRu NPs and Au NPs produced an intense electromagnetic field, which further enhanced the electrooxidation signals of AuRu NPs. An AuRu–Au NP assembly-dependent electrochemical aptasensor was established for the accurate detection of HER2, and the limit of detection (LOD) was as low as 1.7 pg/mL. The plasmon-enhanced electroactivity mechanism endowed AuRu-based nanostructures with strong and noninterfering electrochemical signals for sensitive and accurate detection. This insight opens new horizons for the construction of desired electroactive nanostructures for electroanalysis applications.

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Section: Resultssupporting

confidence: 70%

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confidence: 93%

Plasmon-Enhanced Electroactivity of AuRu Nanostructures for Electroanalysis Applications

et al. 2021

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“…CD-IrNPs were prepared by the reduction of IrCl 3 with NaBH 4 in the presence of β-cyclodextrin, following a similar procedure to that described previously for the synthesis of Cit-IrNPs. 12 The TEM image shows that the as-prepared IrNPs are uniformly dispersed with an average diameter of 1.75 nm (Fig. 1A and S1 †).…”

Section: Resultsmentioning

confidence: 97%

“…10 IrNPs stabilized by citrates (Cit-IrNPs) not only exhibit peroxidase-like properties but also have intrinsic oxidase-like activity. 11,12 In addition, PVP-stabilized IrNPs (PVP-IrNPs) were also reported to have intrinsic catalase-and peroxidase-like activities. 13 Although nanozymes with different elemental compositions, morphologies and properties have been studied, the mechanism behind the enzyme-like properties of nanoparticles is not fully understood.…”

Section: Introductionmentioning

confidence: 99%

The enzymatic performance derived from the lattice planes of Ir nanoparticles

Jin

Sun

et al. 2022

Catal. Sci. Technol.

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“…The ROS involved in the oxidation of the TMB and AR substrates catalyzed by the peroxidase-like activity of NS-C@PtRu were investigated using three scavengers: isopropanol for OH, tryptophane for 1 O 2 , and benzoquinone for O 2 ̄ radicals. [54,55] As shown in Figure 4a, adding isopropanol did not affect the absorbance of the TMB + H 2 O 2 + NS-C@PtRu solution, but adding benzoquinone or tryptophane produced a significant decrease in absorbance. This behavior suggests the involvement of O 2 ̄ and 1 O 2 radicals in the NS-C@PtRu-catalyzed oxidation of TMB.…”

Section: Ros Involved In Ns-c@ptru Peroxidase-like Activitymentioning

confidence: 99%

L‐Cysteine‐Meditated Self‐Assembled PtRu Derived Bimetallic Metal–Carbon Hybrid: An Excellent Peroxidase Mimics for Colorimetric and Fluorometric Detection of Hydrogen Peroxide and Cholesterol

Gupta

Son

Seong

2021

Adv Materials Inter

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Abnormal cholesterol concentrations are related to dyslipidemia, cardiovascular disease, anemia, hypothyroidism, cerebral hemorrhages, and cancer. [2] The primary sources of human cholesterol are diet and synthesis; thus, cholesterol levels can represent the diet and serum spectrum, and are important in food quality control and clinical diagnosing. Various methods, such as colorimetric, enzymatic, fluorometric, chromatographic, and electrochemical approaches, have been proposed for cholesterol quantification. [3,4] Among those methods, indirect cholesterol quantification through an optical analysis of the hydrogen peroxide (H 2 O 2 ) produced by cholesterol oxidation catalyzed by cholesterol oxidase (ChO x ) has proved to be popular and effective. [5,6] In the human body, H 2 O 2 production occurs in response to various enzymatic reactions, and thus it has been suggested as a potential biomarker. [7] Apart from its well-known cytotoxic effects, H 2 O 2 plays a crucial role in many physiological and biological processes, and has significant applications in textiles, cosmetics, agriculture, heavy industry, room decontamination, and food processing. [8] The conventional optical detection methods use natural enzymes (such as horseradish peroxide, HRP), which catalyze H 2 O 2 and produce hydroxyl radicals that oxidize specific substrates and generate readable signals. [3,[9][10][11][12] Although natural enzymes have the advantages of high sensitivity and selectivity, they suffer from complicated immobilization mechanisms, high costs, slow catalytic activity, and low reliability under harsh environmental conditions. [13] When they are used in sensing methods, natural enzymes are particularly vulnerable to interfering substances. [13,14] Therefore, the use of artificial enzymes has gained considerable interest because of their ability to overcome the shortcomings of natural enzymes. [15][16][17][18][19][20][21][22] Since the first artificial enzyme (Fe 3 O 4 ) was discovered, a range of materials has been found to have intrinsic enzymelike activity, including noble metals, transition metals/metal oxides, carbon variants, composites, and metal-organic frameworks. [23][24][25][26] Nanozymes based on metal-carbon hybrids have proven to be particularly effective. [27] Bao et. al. prepared a Artificial enzymes have attracted considerable attention because of their significant advantages over natural enzymes. Herein, the authors report a simple hydrothermal strategy for producing a bimetallic metal -N-, S-doped carbon (NS-C@PtRu) hybrid derived from L-cysteine-mediated self-assembly of PtRu. The peroxidase-like activity and colloidal stability of the NS-C@PtRu are tuned by varying the amount of L-cysteine, the source material for the N-, S-doped carbon. The NS-C@PtRu exhibits good dispersibility, synergistic interactions (metal-metal, metal-carbon), non-metal (N, S) doping, more catalytic active sites, improved noble metallic catalyst performance, and high utilization efficiency. As an excellent peroxidase mimic, NS-C@PtRu ca...

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Ir nanoparticles with multi-enzyme activities and its application in the selective oxidation of aromatic alcohols

Cited by 47 publications

References 43 publications

Plasmon-Enhanced Electroactivity of AuRu Nanostructures for Electroanalysis Applications

Plasmon-Enhanced Electroactivity of AuRu Nanostructures for Electroanalysis Applications

The enzymatic performance derived from the lattice planes of Ir nanoparticles

L‐Cysteine‐Meditated Self‐Assembled PtRu Derived Bimetallic Metal–Carbon Hybrid: An Excellent Peroxidase Mimics for Colorimetric and Fluorometric Detection of Hydrogen Peroxide and Cholesterol

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