Ionophore-Based Ion-Selective Electrodes in Non-Zero Current Modes: Mechanistic Studies and the Possibilities of the Analytical Application

Abstract

This mini review briefly describes (i) literature data on the non-zero current measurements with ionophore-based ion-selective electrodes (ISEs) aimed at fundamental studies of the mechanism of their potentiometric response, and (ii) the data on the possibilities of analytical applications of ISEs in voltametric and constant potential chronoamperometric/coulometric modes, in particular the K+ ion assay in blood serum with the sensitivity of 0.1%. A special attention is paid to the basics of voltammetry and chronoamperometry/coulometry with the ionophore-based ISEs, and to how and why these methods differ from the classical voltammetry and coulometry.

Fabrication of Coupling Approach between Flow Injection System – Ion Selective Electrode

“…The essential, assumption of ICA is that the sources may, be considered as statistically independent random variables. [52] View the details of the ICA strategy used here. Blind source separation (BSS) is a problem for which the Bayes' rule is utilized in order to find a suitable data representation, according to the Bayesian method.…”

“…Among the difficulties in the application of BSS methods to ISE arrays is the fact that the mixing process is nonlinear. [52], [53]…”