Ionomerzement als Knochenersatzmaterial im Mittelohr des Kaninchens

G, Geyer

doi:10.1007/s001060050108

Cited by 13 publications

(15 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Glass-ionomer cement and titanium showed favorable results in preclinical studies in the middle ear of the rabbit [26][27][28]. As in our study, both materials show a good tendency toward epithelialization, with no foreign body reaction or formation of great amounts of fibrous tissue.…”

Section: Discussionsupporting

confidence: 49%

Titanium and Glass-Ionomer Cement as Ossicular Replacement Materials: Biocompatibility Results after Implantation in the Rabbit

Schwager

1998

ORL

Self Cite

View full text Add to dashboard Cite

The middle ear poses unique challenges when finding suitable materials for ossicular reconstruction, primarily because of its link to the external environment via the eustachian tube, which leads to a greater potential for exposure to infectious agents. In this animal study, the biocompatibilities of titanium and glass-ionomer cement were assessed in the middle ear of the rabbit after being implanted as total ossicular replacement prostheses (TORPs) or as free pins. Animals were sacrified after 28, 84, 168, 336, or 504 days or 2 years, and a cutting saw technique was used to prepare slides for light microscopy. Slides were examined for mucosal coverage and any sign of foreign body reaction. Both materials showed good acceptance in the middle ear. After 28 days, the TORPs were covered by middle ear mucosa. As expected, it took a longer time (up to 504 days) to cover the free implants. An interesting finding was the growth of new bone on both the surface of the titanium implants and the glass-ionomer prostheses. The results of this animal study indicate that both titanium and glass-ionomer cement are favorable materials for ossicular replacement prostheses.

show abstract

Section: Discussionsupporting

confidence: 49%

Titanium and Glass-Ionomer Cement as Ossicular Replacement Materials: Biocompatibility Results after Implantation in the Rabbit

Schwager

1998

ORL

Self Cite

View full text Add to dashboard Cite

show abstract

“…As the adhesion to other materials is greater than cohesion, it was not useful to apply more cement than required for a stable connection. More cement does not improve stability, as others have previously shown [1,2,[6][7][8]. Storing the cement in a dry environment caused surface cracking but did not critically impair stability.…”

Section: Minimal Layer Thicknessmentioning

confidence: 56%

“…1,2]. The cement became a subject of critical discussion after several cases of aluminium-induced encephalitis with a fatal outcome [3].…”

Section: Introductionmentioning

confidence: 99%

Advances in the Use of Glass-Ionomeric Cement

Bp¹,

B²,

Strauchmann³

et al. 1998

ORL

View full text Add to dashboard Cite

The objective of this study was to develop a method of cement microapplication using glass-ionomeric cement. The results of an experimental study to design a microapplication method of glass-ionomeric cement (Ionocem^®) are presented. Typical middle ear implant materials, as well as human temporal bones and middle ear ossicles, were used to test the efficiency of this application method. Two different versions of Ionocem^®, low and normal viscosity, were tested under different temperatures and with several application tools. Sufficient processing time could be achieved by cooling the cement down to 4°C. A subcutaneous insulin syringe with a milled-off tip proved to be cost-effective, efficient and versatile. Using this instrument, durable and secure cementation between the parts tested could be achieved. This method may be of significant importance in otologic research and microsurgical routine. In part 2, experimental animal results will follow, as the method portrayed was used to secure parts of a totally implantable middle ear hearing device.

show abstract

“…Das hybride Knochenersatzmaterial Ionomerzement (Ionos, Seefeld bis 12/95; Xomed, Gilching ab 01/96) läßt sich nicht den genannten Werkstoffklassen zuordnen. Es hat sich bei tierexperimentellen Untersuchungen [2,5,13,14,22,25], in der Zellkultur [15,17,24] sowie bei Testung im bakteriell kontaminierten Milieu [19] hinsichtlich Biokompatibilität und Biostabilität bewährt. Die Zwischenbilanz einer prospektiven offenen Studie mit Ionomerzementimplantaten im Mittelohr (n=210 Tympanoplastiken) [6] hatte nach einer maximal 2 1 / 2 jährigen Beobachtungszeit günstige klinische Nachuntersuchungsbefunde und gute audiologische Resultate ergeben.…”

Section: Klinische Prüfungunclassified

“…

Werkstoff, Operationsprinzip und NachbehandlungAuf die wesentlichen Werkstoffcharakteristika wurde im vorausgehenden Artikel [5] hingewiesen. Die zunächst selbstgegossenen und sterilisierten Implantatrohlinge aus Ionomerzement wurden bald von kommerziell gefertigten und inzwischen patentierten Prothesen (Europäische Patentanmeldung vom 03.

…”

unclassified

Ionomerzementprothesen in der rekonstruktiven Mittelohrchirurgie

Helms

1997

HNO

Self Cite

View full text Add to dashboard Cite

Animal experiments with microbiologic examinations and studies in cell cultures have shown that ionomer cement is a biocompatible and biostable bone replacement material in the head and neck region. Clinical and functional results of its use in the human middle ear have proven to be satisfactory during a maximal period of 2.5 years observation. The present trial was continued in order to determine the long-term behavior of ionomer cement (Ionos partial and total ossicles) after reconstruction of the ossicular chain. The ossicular chain was reconstructed in 343 cases and included various losses of one or more of the ossicles (i.e., incus, incus and malleus, incus and stapes superstructure, and malleus, incus and stapes superstructure). Follow-up extended over a maximum period of 5.5 years. Patients were examined under a surgical microscope and a pure-tone audiogram was performed at regular intervals. Clinical and audiological results were obtained 3 months postoperatively in all reconstructive procedures performed (partial and total ossicular replacement prostheses). These were mainly stable but revision surgery was necessary in 9% of the cases. In 5% the prosthesis was displaced and in 3% the prosthesis had partially migrated through the eardrum. Complete rejection of the implants was observed in the course of infections in 1% of the cases. Ionomer cement as a bone replacement material was found to have all required criteria for its use in the middle ear (biocompatibility, biostability, stable audiologic results and easy workability). These findings show that ionomer cement can be recommended in all cases of ossicular reconstruction.

show abstract

Ionomerzement als Knochenersatzmaterial im Mittelohr des Kaninchens

Cited by 13 publications

References 6 publications

Titanium and Glass-Ionomer Cement as Ossicular Replacement Materials: Biocompatibility Results after Implantation in the Rabbit

Titanium and Glass-Ionomer Cement as Ossicular Replacement Materials: Biocompatibility Results after Implantation in the Rabbit

Advances in the Use of Glass-Ionomeric Cement

Ionomerzementprothesen in der rekonstruktiven Mittelohrchirurgie

Contact Info

Product

Resources

About