Ionizing Radiation Effect on Morphology of PLLA: PCL Blends and on Their Composite with Coconut Fiber

Kodama, Yasko; Giovedi, Claudia

doi:10.5772/36473

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Poly(lactic acid) (PLA) has been receiving much attention in the last decades due to its biodegradability in the human body as well as in the soil, biocompatibility, environmentally friendly characteristics, and nontoxicity. − Poly(lactic acid) (PLA) is a highly versatile biodegradable material derived from completely renewable resources (like corn, sugar beet, wheat, and other starch-rich products), and its applications were initially oriented toward the manufacture of medical grade sutures, implants, and controlled drug release applications mainly because of its high costs. Actually, PLA has many potential uses including medical and textile industries, as well as the packaging industry …”

Section: Introductionmentioning

confidence: 99%

Lactoferrin-Immobilized Surfaces onto Functionalized PLA Assisted by the Gamma-Rays and Nitrogen Plasma to Create Materials with Multifunctional Properties

Stoleru¹,

Zaharescu

Hitruc³

et al. 2016

ACS Appl. Mater. Interfaces

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Both cold nitrogen radiofrequency plasma and gamma irradiation have been applied to activate and functionalize the polylactic acid (PLA) surface and the subsequent lactoferrin immobilization. Modified films were comparatively characterized with respect to the procedure of activation and also with unmodified sample by water contact angle measurements, mass loss, X-ray photoelectron spectroscopy (XPS), attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), atomic force microscopy (AFM), and chemiluminescence measurements. All modified samples exhibit enhanced surface properties mainly those concerning biocompatibility, antimicrobial, and antioxidant properties, and furthermore, they are biodegradable and environmentally friendly. Lactoferrin deposited layer by covalent coupling using carbodiimide chemistry showed a good stability. It was found that the lactoferrin-modified PLA materials present significantly increased oxidative stability. Gamma-irradiated samples and lactoferrin-functionalized samples show higher antioxidant, antimicrobial, and cell proliferation activity than plasma-activated and lactoferrin-functionalized ones. The multifunctional materials thus obtained could find application as biomaterials or as bioactive packaging films.

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