Ionized Magnesium and Calcium Levels in Umbilical Cord Serum of Pregnant Women With Transient Hypertension During Labor

Sm, Handwerker; Altura, Bella T.; Royo, Blas; Bm, Altura

doi:10.1093/ajh/6.6.542

Cited by 23 publications

(3 citation statements)

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“…Observing the data in column 3 of Table 2, it becomes evident that the magnesium content in tumor masses and healthy tissues shows minimal variance, aligning within the range of 7.62 to 16.92 ppm in breast tissue and 38.62 to 55.71 ppm in colon tissue. These values adhere consistently to established references [67][68][69][70][71][72][73]. Meanwhile, column 4 of the same table details the magnesium quantities in stage 2A tumors, and column 5 computes the corresponding Mg-28 activity.…”

Section: Discussionsupporting

confidence: 78%

Untitled

2023

Japan J Med Sci

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In this study, we have introduced a novel approach to cancer treatment involving the deactivation of metalloenzymes through the utilization of radioisotopes. The concept of leveraging radioisotopes to interact with metalloenzymes represents a groundbreaking theoretical advancement. Through simulations utilizing the MIRD code and based on the consistent concentration of stable Mg within stage 2A cancerous tissue, we have quantified the potential success rates.To conduct these simulations, we employed 0.1 nanograms (ng) of stable Mg, which corresponds to an activity of 19.7 MBq of Mg-28 radioisotope. This data was input into the MIRD calculations to estimate the absorbed doses within various organs, employing diverse methods of radioisotope administration into the body. Remarkably, even with a mere 0.1% probability of effectively reaching the intended cancerous tissues, this quantity of Mg-28 demonstrates the capability to render billions of Mg-containing metalloenzymes inactive.The remarkable efficiency achieved through precise radioisotope targeting underscores the promise of this methodology. Nevertheless, the findings underscore the necessity of undertaking both in vitro and in vivo research initiatives prior to embarking on clinical trials.

show abstract

Section: Discussionsupporting

confidence: 78%

Untitled

2023

Japan J Med Sci

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show abstract

“…Observing the data in column 3 of Table 2, it becomes evident that the magnesium content in tumor masses and healthy tissues shows minimal variance, aligning within the range of 7.62 to 16.92 ppm in breast tissue and 38.62 to 55.71 ppm in colon tissue. These values adhere consistently to established references [68][69][70][71][72][73]. Meanwhile, column 4 of the same table details the magnesium quantities in stage 2A tumors, and column 5 computes the corresponding Mg-28 activity.…”

Section: Iii2 Discussionsupporting

confidence: 77%

Nuclear Transformation In Metalloenzyme. A Novel And High Potential Cancer Treatment Research

Van Luyen,

Tuan

2023

Preprint

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In this study, we have introduced a novel approach to cancer treatment involving the deactivation of metalloenzymes through the utilization of radioisotopes. The concept of leveraging radioisotopes to interact with metalloenzymes represents a groundbreaking theoretical advancement. Through simulations utilizing the MIRD code and based on the consistent concentration of stable Mg within stage 2A cancerous tissue, we have quantified the potential success rates. To conduct these simulations, we employed 0.1 nanograms (ng) of stable Mg, which corresponds to an activity of 19.7 MBq of Mg-28. This data was input into the MIRD calculations to estimate the absorbed doses within various organs, employing diverse methods of radioisotope administration into the body. Remarkably, even with a mere one thousandth probability of effectively reaching the intended cancerous tissues, this quantity of Mg-28 demonstrates the capability to render billions of Mg-containing metalloenzymes inactive. The remarkable efficiency achieved through precise radioisotope targeting underscores the promise of this methodology. Nevertheless, the findings underscore the necessity of undertaking both in vitro and in vivo research initiatives prior to embarking on clinical trials.

show abstract

“…Observing the data in column 3 of Table2, it becomes evident that the magnesium content in tumor masses and healthy tissues shows minimal variance, aligning within the range of 7.62 to 16.92 ppm in breast tissue and 38.62 to 55.71 ppm in colon tissue. These values adhere consistently to established references[68][69][70][71][72][73]. Meanwhile, column 4 of the same table details the magnesium quantities in stage 2A tumors, and column 5 computes the corresponding Mg-28 activity.…”

supporting

confidence: 82%

Nuclear Transformation In Metalloenzyme. A Novel And High Potential Cancer Treatment Research

Tran,

Hoang

2023

Preprint

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In this study, we have introduced a novel approach to cancer treatment involving the deactivation of metalloenzymes through the utilization of radioisotopes. The concept of leveraging radioisotopes to interact with metalloenzymes represents a groundbreaking theoretical advancement. Through simulations utilizing the MIRD code and based on the consistent concentration of stable Mg within stage 2A cancerous tissue, we have quantified the potential success rates. To conduct these simulations, we employed 0.1 nanograms (ng) of stable Mg, which corresponds to an activity of 19.7 MBq of Mg-28. This data was input into the MIRD calculations to estimate the absorbed doses within various organs, employing diverse methods of radioisotope administration into the body. Remarkably, even with a mere 1‰ probability of effectively reaching the intended cancerous tissues, this quantity of Mg-28 demonstrates the capability to render billions of Mg-containing metalloenzymes inactive. The remarkable efficiency achieved through precise radioisotope targeting underscores the promise of this methodology. Nevertheless, the findings underscore the necessity of undertaking both in vitro and in vivo research initiatives prior to embarking on clinical trials.

show abstract

Ionized Magnesium and Calcium Levels in Umbilical Cord Serum of Pregnant Women With Transient Hypertension During Labor

Cited by 23 publications

References 0 publications

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Nuclear Transformation In Metalloenzyme. A Novel And High Potential Cancer Treatment Research

Nuclear Transformation In Metalloenzyme. A Novel And High Potential Cancer Treatment Research

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