Ionized and total magnesium level in blood serum and plasma of healthy and III adults

Abstract

Ionized magnesium was measured potentiometrically using a clinical analyzer MICROLYTE 6 (KONE, Finland). Total magnesium was measured colorimetrically. Ionized magnesium (iMg) concentration changes with pH were made to observe the accuracy of the results if they were not recalculated to the actual pH of blood or recalculated with some uncertainty in parameters. The dependence of iMg and iCa on heparin (used as anticoagulant in plasma samples) was made. Less than 40 units per 1 mL of blood decreased the concentration of iMg and iCa less than 1.5%. The range of iMg and total Mg in serum and plasma of healthy and ill adults (short bowel syndrome, myocardial infarct) was investigated and compared. In both illnesses, the concentration of ionized and/or total magnesium is significantly different from the range of healthy people. The range of iMg and total Mg as well as the percentage of iMg against total Mg seem to be specific for a given illness.

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