Ionic Liquids: Improved Syntheses and New Products

Carmichael, Adrian J.; Deetlefs, Maggel; Earle, Martyn J.; Fröhlich, Ute; Seddon, Kenneth R.

doi:10.1021/bk-2003-0856.ch002

Cited by 17 publications

(4 citation statements)

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“…1 The distinct physicochemical features of ILs, i.e., negligible vapor pressure, non-flammability, high chemical/thermal stability, low toxicity, favorable conductivity and controllable hydrophobicity/hydrophilicity have indicated great promise as attractive green alternatives to or replacements for conventional volatile organic solvents. In addition, increasing applications of the ILs as benign media in organic synthesis, 2,3 extraction/separation, 4,5 electrochemical studies, 6 solar cells, 7 gas sensors 8 as well as other applications are evident from the recent literatures.…”

Section: Introductionmentioning

confidence: 99%

Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Chen

Wang

2010

Analyst

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The crystallization of lysozyme with hydrophilic ionic liquid 1,3-butylimidazolium chloride (BBimCl) as an additive was investigated with hanging-drop vapor diffusion crystallization protocol. The elevated threshold to super-saturation caused by the increased solubility of lysozyme in the presence of BBimCl and the slower super-saturation process of lysozyme induced by the negligible vapor pressure of BBimCl contributed to a lower super-saturation degree, offering a promoted ambient circumstance for nucleation and providing a controlled velocity for the growth of lysozyme crystal. These eventually offer a prominent promotion to the crystallization of lysozyme, i.e., less crystal polymorphism and precipitation while larger crystals and significantly improved the tolerance to the concomitant impurities or sample matrices for the crystallization of lysozyme. Therefore, the presence of BBimCl enables the direct crystallization of lysozyme from a real complex sample matrix, i.e., egg-white, which opens a promising avenue for the development of protein crystallization methodology with ionic liquids as an additive and offers vast potentials for the practical separation/purification of proteins of interest from complex real sample matrices.

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Section: Introductionmentioning

confidence: 99%

Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Chen

Wang

2010

Analyst

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“…Synthesis and Characteriz ation. Generally the synthesis of most ionic liquids consists of a quaternization step followed by a metathesis stepanion exchange . All the procedures used were standard literature ones with slight modifications.…”

Section: Resultsmentioning

confidence: 99%

Decolorization of Ionic Liquids for Spectroscopy

et al. 2006

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It has been widely recognized that although ionic liquids should be colorless, they are frequently not. Colored samples appear to be pure by most analytical techniques (e.g., NMR spectroscopy, mass spectrometry, HPLC, and ion chromatography), and there have been many attempts to identify the source of color in our own laboratories and others-after 20 years the best that can be said is that the impurities are at a very low level (probably parts per billion) with very high molar extinction coefficients. In this paper, we do not identify these impurities but describe a practical method for removing them for spectrochemical applications. We clearly note that the method is not "green", but we anticipate that it will only be applied to the small volumes of ionic liquids required for fundamental spectroscopic studies in academia but not in industrial processes.

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“…Materials. Ionic liquids, 19 HRhCO(PPh 3 ) 3 catalyst, 20 and RuCl 2 (PPh 3 ) 3 21 catalyst were prepared according to reported methods and characterized by nuclear magnetic resonance (NMR) spectroscopy (Varian 400-MHz) and Fourier transform infrared (FT-IR) spectroscopy (Perkin-Elmer 100 Spectrochem Series). Silica gel was procured from Sigma-Aldrich (Merck grade, with a BET surface area of 675 m 2 /g, a particle size of 35-70 mesh (200-500 µm), a mean pore size of 40 Å, and a pore volume of 68 cm 3 /g), and allylic alcohols were purchased from Lancaster.…”

Section: Methodsmentioning

confidence: 99%

Regioselective Hydroformylation of Allylic Alcohols Using Rh/PPh₃ Supported Ionic Liquid-Phase Catalyst, Followed by Hydrogenation to 1,4-Butanediol Using Ru/PPh₃ Supported Ionic Liquid-Phase Catalyst

Panda

Jagtap

Nandurkar

et al. 2008

Ind. Eng. Chem. Res.

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The regioselective hydroformylation of allyl alcohol was performed using conventional Rh/PPh3 catalyst in an ionic liquid film supported on silica (Rh/PPh3/SILPC), with water as a reaction medium. Subsequently, the hydroformylation products were hydrogenated using a Ru/PPh3/SILP catalyst to give 1,4-butanediol. The effects of various reaction parameters such as the P/Rh ratio, the substrate/Rh ratio, the temperature, the pressure, and various immobilizing agents on the chemoselectivity and regioselectivity for hydroformylation of allyl alcohol were studied. Extension of this methodology to the hydroformylation of various methyl-substituted allylic alcohols was also studied. Very high conversion and selectivity toward n-aldehyde can be achieved using the present heterogenized homogeneous catalyst system.

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Ionic Liquids: Improved Syntheses and New Products

Cited by 17 publications

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Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Decolorization of Ionic Liquids for Spectroscopy

Regioselective Hydroformylation of Allylic Alcohols Using Rh/PPh₃ Supported Ionic Liquid-Phase Catalyst, Followed by Hydrogenation to 1,4-Butanediol Using Ru/PPh₃ Supported Ionic Liquid-Phase Catalyst

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Ionic Liquids: Improved Syntheses and New Products

Cited by 17 publications

References 0 publications

Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Improvement on the crystallization of lysozyme in the presence of hydrophilic ionic liquid

Decolorization of Ionic Liquids for Spectroscopy

Regioselective Hydroformylation of Allylic Alcohols Using Rh/PPh3 Supported Ionic Liquid-Phase Catalyst, Followed by Hydrogenation to 1,4-Butanediol Using Ru/PPh3 Supported Ionic Liquid-Phase Catalyst

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Regioselective Hydroformylation of Allylic Alcohols Using Rh/PPh₃ Supported Ionic Liquid-Phase Catalyst, Followed by Hydrogenation to 1,4-Butanediol Using Ru/PPh₃ Supported Ionic Liquid-Phase Catalyst