Ionic wind is a phenomenon of electrofluid movement in electrostatic precipitator, which changes the motion state of flue gas and dust in electrostatic precipitator to a certain extent. In order to study the influence of ionic wind on air flow characteristics in electrostatic precipitator, this paper constructed a numerical model of electric field-flow field coupling and compared the impact of electro-hydro dynamics (EHD) effect on flue gas flow state at different inlet velocities. In addition, this paper analyzed the influence of EHD effect on the motion trajectories of particles with different sizes. The results showed that the EHD effect changed the flue gas flow field near the anode plate at 0.3m/s inlet velocity, forming an obvious reflux region; this phenomenon weakened when the inlet velocity increased. At the same time, the EHD effect reduced the dust removal efficiency when the particle radius ranged from 0.25 μm to 1 μm.