Using a laser polarization gradient, we realize 3D Sisyphus cooling of 171 Yb + ions confined in and near the Lamb-Dicke regime in a linear Paul trap. The cooling rate and final mean motional energy of a single ion are characterized as a function of laser intensity and compared to semiclassical and quantum simulations. Sisyphus cooling is also applied to a linear string of four ions to obtain a mean energy of 1-3 quanta for all vibrational modes, an approximately order-of-magnitude reduction below Doppler cooled energies. This is used to enable subsequent, efficient sideband laser cooling.PACS numbers: 37.10. De, 37.10.Ty Applications of laser-cooled, trapped ions range from quantum information processing [1][2][3][4][5][6] and spectroscopy and metrology [7][8][9][10] to the study of interactions with cold atoms [11][12][13] and the study of few-body "phase transitions" [14][15][16][17][18]. Central to many of these applications is the manipulation of the collective vibrational modes of a string of Coulomb-coupled ions. The modes of interest are often required to be prepared in their quantum mechanical ground state, which is commonly achieved with sideband laser cooling [19][20][21] or electromagnetically induced transparency (EIT) cooling [22,23]. In practice, these techniques are implemented for reasons of efficiency in the Lamb-Dicke regime, where the ions' residual amplitude of vibration is small compared to the wavelength of the cooling laser [2,24,25]. Doppler laser pre-cooling is usually sufficient to attain this condition, but if the trap is somewhat weaker, the ions will not begin close to the ground state, or deep in the LambDicke regime. In the case of Raman-transition sideband cooling [20], this lengthens and complicates the sequence to walk the vibrational modes down the ladder of energy levels. Here we consider Sisyphus laser cooling [26,27], well known for neutral atoms, to act as a bridge between Doppler and ground-state laser cooling for ions. This relaxes the requirement on trapping strength, which is of technological relevance for larger mass ions, and for the weaker axial confinement necessary to maintain linear strings of larger ion number. As a convenient means to reach near-ground-state energies, Sisyphus cooling of trapped ions is a technique of potential broad applicability in analogy with experiments with neutral atoms.Since Sisyphus cooling was first demonstrated in a 3D optical molasses [28], the technique has been widely adopted to cool neutral atomic gasses to sub-Doppler temperatures [29]. Sisyphus cooling, primarily due to polarization gradients, has also been used for the cooling and localization of atoms in optical lattices [30][31][32][33][34], optical cavities [35,36] and optical tweezers [37][38][39]. Several theoretical investigations, both semiclassical and quantum, have extended the concept of Sisyphus cooling to a single ion confined in the Lamb-Dicke regime, with proposals considering cooling in both intensity [40,41] and polarization [42,43] gradients. Semiclassical ...