Ion-pair extraction and determination of copper(II) and zinc(II) in environmental and pharmaceutical samples

Malvankar, Purnima L.; Shinde, V. M.

doi:10.1039/an9911601081

Cited by 127 publications

(47 citation statements)

References 8 publications

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“…Preconcentration and separation can solve these problems and lead to a higher confidence level and easy determination of trace elements by less sensitive, but more accessible, instrumentation, such as flame atomic absorption spectrometry (AAS). 10 There are many methods of preconcentration and separation, such as liquidliquid extraction (LLE), 11 ion-exchange techniques 12 and solid phase extraction (SPE) with various adsorbents. 13,14 However, these methods need high volumes of the samples, which are unsuitable for biological samples.…”

Section: Introductionmentioning

confidence: 99%

Sensitive and Simple Cloud-point Preconcentration Atomic Absorption Spectrometry: Application to the Determination of Cobalt in Urine Samples

Manzoori

Karim‐Nezhad

2003

ANAL. SCI.

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A new approach for developing a cloud-point extraction-flame atomic absorption spectrometric method has been described and used for the determination of cobalt. In this approach, water was removed from the final diluted surfactant rich phase obtained in cloud-point extraction procedure. The results indicated that removing water from this phase increased the enhancement factor by 4-fold. 1-(2-Pyridylazo)-2-naphthol (PAN) and octylphenoxypolyethoxyethanol (Triton X-114) were used as a hydrophobic ligand and a nonionic surfactant, respectively. The chemical variables affecting the preconcentration step were optimized. The effect of the water concentration in the final diluted methanolic surfactant solution on the analytical signal was investigated. The results showed that the analytical signal decreased by 30% and 52% in 15% and 25% water concentrations in methanol, respectively. An enhancement factor of 115 was obtained for cobalt extracted from only 10 ml of a sample. The detection limit obtained under the optimal condition was 0.38 µg l -1 . The proposed procedure was applied to the determination of cobalt in urine samples.

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Section: Introductionmentioning

confidence: 99%

Sensitive and Simple Cloud-point Preconcentration Atomic Absorption Spectrometry: Application to the Determination of Cobalt in Urine Samples

Manzoori

Karim‐Nezhad

2003

ANAL. SCI.

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“…The most widely used techniques for the separation and preconcentration of trace elements include liquid-liquid extraction, 5,6 solid-phase extraction, 7-10 coprecipitation, 11,12 ionexchange, 13 evaporation 14 and electrochemical deposition. 15 Recently, the solid-phase extraction (SPE) technique has become increasingly popular compared with the more traditional liquid-liquid extraction methods.…”

Section: Introductionmentioning

confidence: 99%

ICP-AES Detection of Ultratrace Aluminum(III) and Chromium(III) Ions with a Microcolumn Preconcentration System Using Dynamically Immobilized 8-Hydroxyquinoline on TiO2 Nanoparticles

Liang

Yang

et al. 2003

ANAL. SCI.

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Titanium dioxide nanoparticle dynamically loaded with 8-hydroxyquinoline (nanometer TiO2-Oxine) was used as a solidphase extractant for the preconcentration of trace amounts of aluminum(III) and chromium(III) prior to their determination by inductively coupled plasma atomic emission spectrometry (ICP-AES). The optimal conditions for preparing nanometer TiO2-Oxine were obtained. Also, the separation/preconcentration conditions of analytes, including the effects of the pH, the sample flow rate and the volume, the elution solution and the interfering ions on the recovery of the analytes were investigated. At pH 6.0, the adsorption capacity of nanometer TiO2-Oxine was found to be 5.23 mg g -1 and 9.58 mg g -1 for Al(III) and Cr(III), respectively. An enrichment factor of 50 was achieved by this method, and the detection limits (3σ) for Al(III) and Cr(III) were 1.96 and 0.32 µg L -1 respectively. The proposed method was applied for the determination of trace Al(III) and Cr(III) in biological samples and lake water with satisfactory results.

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“…It is a cofactor and/or a structural component of numerous enzymes and other proteins needed in metabolic processes. 1 However, the accumulation of Cu 2+ in humans leads to many serious conditions, including neurodegenerative diseases and prion diseases. 2,3 As such, the detection and measurement of Cu 2+ has become increasingly important.…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive detection of Cu2+ with the naked eye and application in immunoassays

Lü

Wang

et al. 2012

NPG Asia Mater

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In this study, a novel method for the fast, sensitive and selective detection of Cu 2+ using gold nanoparticles (AuNPs) was developed and used in immunoassays. In the presence of L-cysteine, L-cysteine can bind to the surface of citrate-stabilized AuNPs through Au-S bonds. As a result, aggregation of AuNPs occurs through electrostatic interactions between the cysteinebound AuNPs. In contrast, in the presence of Cu 2+ , Cu 2+ can catalyze O 2 oxidation of cysteine, leading to the quick formation of disulfide cystine. An increase in the concentration of Cu 2+ decreased L-cysteine-induced AuNPs aggregation by decreasing the number of free cysteine thiol groups, and the solution color changed from purple to red. Therefore, the concentration of Cu 2+ can be detected with the naked eye or with ultraviolet-visible spectroscopy, and the detection limits of Cu 2+ were 20 nM and 10 nM, respectively. This sensitivity was approximately three orders of magnitude higher than that of traditional AuNPs-based colorimetric Cu 2+ detection methods. Because of the high sensitivity of the proposed method, we further used it with a labeled antibody in colorimetric immunoassays. The detection limit of the cancer biomarker a-fetoprotein was 2 ng ml À1 , which is comparable to the detection limit of the enzyme-linked immunosorbent assay method. INTRODUCTIONCopper is an essential metal ion for biological functions. It is a cofactor and/or a structural component of numerous enzymes and other proteins needed in metabolic processes. 1 However, the accumulation of Cu 2+ in humans leads to many serious conditions, including neurodegenerative diseases and prion diseases. 2,3 As such, the detection and measurement of Cu 2+ has become increasingly important. To date, there are many technologies that have been developed to detect Cu 2+ , including inductively coupled plasma 4 detectors, electrochemical sensors, 5 surface-plasmon resonance 6 detectors, fluorescenceanisotropy assays, 7 quantum-dot-based assays 8 and Cu 2+ -specificDNAzyme-based fluorescence sensors. 9 Although these technologies can detect Cu 2+ sensitively and selectively, the need for sophisticated instrumentation and highly trained operators limited their application in routine detection.Recently, gold-nanoparticles (AuNPs)-based colorimetric methods, which without the aid of advanced instrumentation, have attracted attention for their use in many applications because they can be easily monitored with the naked eye or with low-cost portable instruments. AuNPs possess intrinsically strong surface-plasmon resonance absorptions and high extinction coefficients (approximately four orders of magnitude greater than typical organic dyes). 10 The color of the AuNPs solution can change from red to purple, in response to the surface-plasmon resonance absorption of dispersed and aggregated

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Ion-pair extraction and determination of copper(II) and zinc(II) in environmental and pharmaceutical samples

Cited by 127 publications

References 8 publications

Sensitive and Simple Cloud-point Preconcentration Atomic Absorption Spectrometry: Application to the Determination of Cobalt in Urine Samples

Sensitive and Simple Cloud-point Preconcentration Atomic Absorption Spectrometry: Application to the Determination of Cobalt in Urine Samples

ICP-AES Detection of Ultratrace Aluminum(III) and Chromium(III) Ions with a Microcolumn Preconcentration System Using Dynamically Immobilized 8-Hydroxyquinoline on TiO2 Nanoparticles

Ultrasensitive detection of Cu2+ with the naked eye and application in immunoassays

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