Ion Mobility Spectrometry: Ion Source Development and Applications in Physical and Biological Sciences

Guharay, S. K.; Dwivedi, Prabha; Hill, Herbert H.

doi:10.1109/tps.2008.927290

Cited by 61 publications

(40 citation statements)

References 161 publications

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“…IMS is a well-known method to analyze chemical substance using gas-phase mobility in a weak electric field [14][15][16], and is more and more used in the detection of explosives, drugs, chemical warfare agents, biological and medical samples [17][18][19][20][21][22][23][24][25]. Unlike the mass spectrometry [26,27], which operates in vacuum, IMS detects chemical compounds at atmospheric pressure.…”

Section: Introductionmentioning

confidence: 99%

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Han

Cheng

et al. 2012

International Journal of Mass Spectrometry

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Section: Introductionmentioning

confidence: 99%

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Han

Cheng

et al. 2012

International Journal of Mass Spectrometry

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“…(72) For more detailed information on sources compatible with IMS, we refer readers to a recent review on the subject. (73) …”

Section: Othersmentioning

confidence: 99%

Ion Mobility‐Mass Spectrometry

Jiang

Robinson

2013

Encyclopedia of Analytical Chemistry

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Ion mobility spectrometry (IMS) separates ions based on their mobility in an inert buffer gas in the presence of an electric field. The mobility of ions is based on their size, shape, and charge, thus IMS provides insights into structure. In addition to being used for structural information, IMS can also be used as a separation device for complex mixtures. When coupled with mass spectrometry (MS), IMS–MS offers a powerful hybrid analytical technique that has many biological, pharmaceutical, structural, environmental, and other applications. This article provides an overview of IMS–MS, which focuses on principles of drift‐time ion mobility spectrometry (DTIMS), high‐field‐asymmetric ion mobility spectrometry (FAIMS), and traveling wave ion mobility spectrometry (TWIMS) methods. Several IMS–MS instruments are discussed and examples of the current applications of the technology are provided.

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“…For reasons of simplicity, the ionization source in most commercial devices is a radioactive substance: mainly Ni with a maximum value of 18.6 keV and an average value of 5.7 keV (Guharay et al 2008 ). They produce so-called reactant ions via a sequence of reactions, especially with N 2 .…”

Section: Introductionmentioning

confidence: 99%

Pulsed electron beams in ion mobility spectrometry

Baether¹,

Zimmermann²,

Gunzer³

2012

Reviews in Analytical Chemistry

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Abstract:Ion mobility spectrometry is a well-known technique used to analyze trace gases in ambient air. Typically, it works by employing a radioactive source to provide electrons with high energy to ionize the analytes in a series of chemical reactions. During the past ten years non-radioactive sources have been one of the subjects of interest in ion mobility spectrometry, initially in order to replace radioactive sources as a result of general security and regulatory concerns. Among these non-radioactive sources especially pulsed sources have recently been shown to additionally improve the analytic information provided by ion mobility spectrometers. In this review we will describe the progress regarding the application of pulsed non-radioactive electron sources in ion mobility spectrometry and show the recent analytical advances that have been achieved by using pulsed electron beams.

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Ion Mobility Spectrometry: Ion Source Development and Applications in Physical and Biological Sciences

Cited by 61 publications

References 161 publications

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Computational fluid dynamics-Monte Carlo method for calculation of the ion trajectories and applications in ion mobility spectrometry

Ion Mobility‐Mass Spectrometry

Pulsed electron beams in ion mobility spectrometry

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