Boron isotope separation by ion exchange chromatography is characterized by high efficiency, low energy consumption, safe operation and low equipment investment. It is a promising process for industrial scale production. The latest progress for enriching 10 B isotope by ion exchange chromatography is reviewed in this article. Currently, strongly basic anion exchange resins, weakly basic anion exchange resins and boron-specific resins are used as chromatographic column packing materials. With a brief introduction of the separation principle, the advantages and disadvantages of these resins are compared. Some elements influencing the single-stage separation factor are also discussed.