Ion chromatography

Morales‐Rubio, Ángel; Guárdia, Miguel de la

doi:10.1002/9781118654316.ch16

Cited by 2 publications

(2 citation statements)

References 86 publications

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“…In addition to routine analysis of water and wastewater [68], the scope of its applications is rapidly expanding to include new groups of substances and matrices. Examples are metals and metalloids [69,70], food samples [71], and clinical and pharmaceutical samples [72][73][74]. Consequently, IC has rapidly become the reference method for the determination of major inorganic ions in water and wastewater, as well as solid and air samples [75,76].…”

Section: Determination Methods For Glyphosatementioning

confidence: 99%

Ion chromatography for the analysis of glyphosate and its selected metabolites. A review

Michalski

Pecyna-Utylska

2023

J of Separation Science

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Among all known compounds with herbicide activity glyphosate, has been the most commercially successful one. Currently, it is under evaluation because of its possible cancerogenic properties. However, the question is-if it is possible to completely withdraw it from use. Before it can happen, it is important to be sure of all its benefits and limitations, and this requires further detailed research. Due to the extent and prevalence of its use, glyphosate ends up in the environment and then in food and our bodies. There are several methods used for their determination. One of them is ion chromatography. Taking into account its advantages and disadvantages, as well as its rapid development, their importance in this field can be expected to increase in the near future. This paper summarizes the literature data from the past 22 years. The applications of ion chromatography in the determination of glyphosate in various types of environmental, food, and other samples are described. Moreover, the methods used so far are compared with the possibilities offered by ion chromatography, which main advantages and benefits are easy availability, low operating costs, green chemistry aspects, and suitable validation parameters.

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Section: Determination Methods For Glyphosatementioning

confidence: 99%

Ion chromatography for the analysis of glyphosate and its selected metabolites. A review

Michalski

Pecyna-Utylska

2023

J of Separation Science

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“…IC has been used widely for trace level analyses of ions in the environmental and food industry, , but it is largely untested for separating ionic and polar compounds in metabolomics research. A few applications have coupled IC to mass spectrometry (MS) for global profiling or quantitation of phosphate sugars, OAs, and nucleotides in biological samples. − Herein, we showed IC/MS to be a highly selective and sensitive complementary approach to other modes of chromatography for quantitating a broad range of 28 polar, low molecular weight OAs.…”

mentioning

confidence: 99%

Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic Acids

et al. 2016

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Organic acids (OAs) serve as metabolites that play pivotal roles in a host of different metabolic and regulatory pathways. The polar nature of many OAs poses a challenge to their measurement using widely practiced analytical methods. In this study, a targeted metabolomics method was developed using ion chromatography/triple quadrupole mass spectrometry (IC/MS) to quantitate 28 polar OAs with limits of quantitation ranging from 0.25 to 50 μM. The interday assay precisions ranged from 1% to 19%, with accuracies ranging from 82% to 115%. The IC/MS assay was used to quantitate OAs in quadriceps muscle from sedentary mice compared to fatigued mice subjected to either a low intensity, long duration (LILD) or high intensity, short duration (HISD) forced treadmill regimen. Among the OAs examined, significant differences were detected for hippuric acid, malic acid, fumaric acid, and 2-ketoglutaric acid between the sedentary and fatigued mice. In conclusion, the IC/MS method enabled the separation and quantitative survey of a broad range of polar OAs that are difficult to analyze by chromatographic techniques.

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Ion chromatography

Cited by 2 publications

References 86 publications

Ion chromatography for the analysis of glyphosate and its selected metabolites. A review

Ion chromatography for the analysis of glyphosate and its selected metabolites. A review

Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic Acids

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