Ion chromatographic determination of salicylate in human serum with a bulk acoustic wave sensor as detector

Yu, Bing-Sheng; Shou‐Zhuo, Tao

doi:10.1002/jhrc.1240200409

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Electrochemical Biosensors for Salicylate and Its Derivatives

Neto¹,

Júnior

Kubota

1999

Electroanalysis

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Several methods have been employed for the quanti®cation of salicylate and related compounds in many kinds of matrices. Special interest has been devoted over the last few years to the development of biosensors involving electrochemical techniques, due to the great selectivity and sensitivity offered by these probes. The main electroanalytical methods developed for salicylate determination in samples of clinical, biological and pharmaceutical interest are described here. A review of the most relevant advances in analytical applications of biosensors using electrochemical transducers is also described. Particular attention is dedicated to the essential advantages supplied by amperometric sensors obtained by incorporation of the bioactive elements into supporting materials, like conducting polymers, for the construction of salicylate biosensors. Some correlation between analytical parameters, such as stability and linear response range for these probes, are discussed.

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