Iodomethane in C1 chemistry: application in palladium-catalyzed [2 + 2 + 1] annulation

Abstract

A variety of chromone-containing polycyclic compounds were smoothly forged in up to 93% yield via palladium-catalyzed [2 + 2 + 1] annulation of 3-iodochromones, bridged olefins, and iodomethane, in which iodomethane was used as the methylene source.