Iodine-enabled organoelectrocatalysis: enantioselective cross dehydrogenative coupling of sulfides and aldehydes

Abstract

A method for the direct asymmetric α-sulfenylation of aldehydes with sulfides was developed.

Electrochemical aminotrideuteromethylthiolation of isocyanides with anilines and CD3SSO3Na

“…Initially, I 2 is formed by the anodic oxidation of the iodide ion. 14 Sulfenyl iodide is then generated via the reaction of I 2 with CD 3 SSO 3 Na. 15 Then, the resulting CD 3 SI undergoes a homolysis step and produces iodine and CD 3 S radicals.…”