Iodine Deficiency Disorders

Semba, Richard D.; Delange, François

doi:10.1007/978-1-59745-464-3_17

Cited by 4 publications

(2 citation statements)

References 88 publications

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“…For example, deficiency in vitamin A can lead to immunosuppression and blindness; iron deficiency can lead to anemia; and iodine deficiency can lead to goiter (Ramakrishnan and Semba 2008, Semba and Delange 2008, West and Darnton-Hill 2008.…”

Section: What Is Food Utilization?mentioning

confidence: 99%

Climate Change, Global Food Security, and the U.S. Food System

Brown¹,

Antle²,

Backlund³

et al. 2015

162

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Section: What Is Food Utilization?mentioning

confidence: 99%

Climate Change, Global Food Security, and the U.S. Food System

Brown¹,

Antle²,

Backlund³

et al. 2015

162

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“…Hypothyroidism or hyperthyroidism caused by supraphysiologic iodine exposure might be asymptomatic or overt, and the source of extra iodine isn't always obvious. 5 Since iodine deficiency disorders involving the thyroid gland are commonly encountered in the population, we have undertaken this study. In this study we have proposed to investigate the association of iodine status among the population with thyroid glandular dysfunctions.…”

Section: Introductionmentioning

confidence: 99%

Biochemical and Clinical Characterization of Iodine Deficiency Disorders in Central India

Yembarwar¹,

Guddetwar

2022

IJMBS

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Background: Iodine (I) is a trace element that is required by both humans and animals. It can be found in a variety of chemical forms, including iodine, iodide (I), and iodate (IO3). It is widely distributed across the earth's ecology, with a concentration in the oceans. Iodine entered the natural cycle from the ocean, the atmosphere, and rainfall, as well as from rainfall into streams and rivers. Iodine is absorbed as iodide in human nutrition. Iodine is a necessary micronutrient and a component of thyroid hormones. Fish and seafood have a high iodine level. The amount of iodine in soil and drinking water varies depending on where it comes from. Iodine shortage produces a variety of negative health consequences, which are referred to as iodine deficiency illnesses (IDD). These conditions are caused by a lack of iodine, which causes insufficient thyroid hormone production. Aim: The aim of this study is to characterize the iodine deficiency disorder by biochemical and clinical assessment and to correlate the iodine status with thyroid disorder(s) in adults. Material and Method: The samples for this investigation were taken from patients at the Department of Endocrine Surgery. This study comprised a total of 100 hundred goiter patients, who had their urinary iodine excretion and thyroid hormone levels examined. For all goiter patients, the grading of goitre was established using the WHO/UNICEF/ICCIDD approved criteria. TSH, Free T4, Free T3 by using ELISA Method using commercial kits. Anti-microsomal antibody (AMA) or Thyroperoxidase antibody (TPO-Ab) by using ELISA Method using commercial kits. Anti-thyroglobulin antibody (ATG) estimated by using ELISA Method using commercial kits. Results: The data for each group were presented as Median and inter quarter range (IQR) The median and IQR of Urinary iodine excretion of the hypothyroid, hyperthyroid and Euthyroid goiter subjects were respectively and there was significant difference in the median urinary iodine excretion. The median and IQR of Urinary iodine excretion of the thyroiditis, thyrotoxicosis, cancer of thyroid and benign goiter respectively and there was significant difference in the median urinary iodine excretion. Conclusion: For ages, endemic goitre and cretinism have been recognised as public health issues, and iodine deficiency is thought to be the leading cause of preventable mental retardation. Most countries now include iodine deficiency control as part of their national nutrition policies. To eliminate iodine deficiency, several therapies with high efficacy have been employed, including iodized oil capsules (IOC) and universal salt iodisation (USI). Although some progress has been made, efforts to eliminate this devastating health problem must be hastened. Not only should iodine deficiency be monitored, but so should excessive iodine intake, as this is a problem in various areas, including the camps. Keywords: IDD, Goitre, TSH, IOC, USI, ATG, AMA, T4, T3.

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Voltammetric determination of iodide in iodized table salt using cetyltrimethylammonium bromide as ion-pairing

et al. 2019

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In this work, voltammetric study based on cetyltrimethylammonium bromide (CTAB) as an ion-pairing agent for the determination of iodine level in iodized table salt has been explored. CTAB was used as an intermediate compound between iodide (I -) and the electrode due to its ability to dissociate to produce cetyltrimethylammonium ions ([CTA] ? ). The [CTA] ? with a long hydrophobic alkyl chain can be directly adsorbed onto the surface of the working electrode, and this in turns coated the electrode with cationic charge and enhance the electrode ability to bind to iodide (I -) and other molecular iodine ions. A mixture of iodide and CTAB ([CTA] ? I -) was prepared and potential of 1.0 V for 60.0 s was applied to pre-concentrate the solution on the working electrode causing the [CTA] ? Ito oxidize to iodine (I 2 ). The produced I 2 immediately react with chloride ion (Cl -) from the electrolyte of hydrochloric acid (HCl) to produce I 2 Cland form ion-pair with CTA ? as [CTA] ? I 2 Cl -. The linear calibration curve of the developed method towards iodide was in the concentration range of 0.5-4.0 mg/L with sensitivity of -1.383 lA mg/L -1 cm -2 (R 2 = 0.9950), limit of detection (LOD) of 0.3 mg/L and limit of quantification (LOQ) of 1.0 mg/L, respectively. The proposed method indicates good agreement with the standard method for iodine determination with recovery range from 95.0 to 104.3%. The developed method provided potential application as a portable on-site iodine detector.

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Iodine Deficiency Disorders

Cited by 4 publications

References 88 publications

Climate Change, Global Food Security, and the U.S. Food System

Climate Change, Global Food Security, and the U.S. Food System

Biochemical and Clinical Characterization of Iodine Deficiency Disorders in Central India

Voltammetric determination of iodide in iodized table salt using cetyltrimethylammonium bromide as ion-pairing

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