Involvement of the nervous system in malignant lymphoma in Nigeria.

Janota, I.

doi:10.1038/bjc.1966.7

Cited by 29 publications

(2 citation statements)

References 8 publications

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“…The higher incidence found in this study when compared to 10% found in a previous study (12) may reflect the present socio-economic climate in the country with the prohibitive cost of treatment, and therefore progression of the disease with brain involvement. Involvement of the brain is usually associated with widespread organ involvement and has a poor prognosis (11).…”

Section: Discussionmentioning

confidence: 99%

Intracranial neoplasmin Ibadan, Nigeria

Bj¹,

Shokunbi²,

Pu³

2009

E Af Med Jrnl

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Objective: To determine the pattern of histopathological variants of intracranial neoplasms, relative distribution of the variants in the age groups and also to determine the gender differences that exist in these tumours. Design: Case control study. Setting: Department of Pathology, University College Hospital, Ibadan, Nigeria. Patients: Two hundred and ten histologically confirmed cases of intracranial neoplasms seen during eleven-year period (1980 to 1990) were analysed. Interventions: Slides of tumours stained with haematoxylin and eosin, reticulin and phosphotungstic acid haematoxylin. Results: Two hundred and ten intracronial neoplasms comprising 172 primary and 48 secondary neoplasms were seen. One hundred and thirty five neoplasms occurred in adults and 75 in children. There was no gender difference, the ratio being 1:1. Gliomas accounted for the largest group of tumours followed by metastases to the brain. Of the gliomas, astrocytoma was the commonest. Craniopharyngiomas were found to be common in children. Germ cell tumours were found to be uncommon. Conclusion: Gliomas are the commonest group of intracranial neoplasms in both adults and children. This is followed by metastatic tumours. Tumours of the sella turcica are predominantly found in children. Involvement of the brain in disseminated Burkitt's lymphomas is predominantly found in Africans as the Burkitt's tumour is uncommon in non Africans.

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Section: Discussionmentioning

confidence: 99%

Intracranial neoplasmin Ibadan, Nigeria

Bj¹,

Shokunbi²,

Pu³

2009

E Af Med Jrnl

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“…Unter den lymphoblastischen Lymphomen im Kindesalter neigen besonders der Burkitt-Typ, das echte Burkitt-Lymphom und das undifferenzierte Lymphom zu einer Meningosis im späteren Verlauf (13,34).…”

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Die Meningosis neoplastica und ihre Prophylaxe bei malignen Non-Hodgkin-Lymphomen

Delbrück¹,

Wetter²,

Schmidt³

et al. 1977

Dtsch med Wochenschr

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Among 334 patients (aged 15-57 years) with malignant non-Hodgkin's lymphoma there were 14 who developed CNS complications, none in 144 with lymphoma of low malignancy. Lymphoblastic lymphoma predominated amoung those with CNS involvement. In adults with this form treatment should therefore be undertaken to prevent such complications. The study confirms the need for histological subclassification in malignant non-Hodgkins's lymphoma.

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Involvement of the central nervous system in non-hodgkin's lymphoma

Law

Dick

Blom

et al. 1975

Cancer

111

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Twenty-four patients with non-Hodgkin's lymphoma and CNS involvement are presented. There were 7 cases with diffuse histiocytic lymphoma (HL), 9 with diffuse poorly differentiated lymphocytic lymphoma (PDLL-D), of whom 6 patients were in leukemic conversion, 5 patients with nodular poorly differentiated lymphocytic lymphoma (PDLL-N), and 3 cases with undifferentiated lymphoma (UL). CNS complications were noted only in Stage IV lymphoma; the prognosis was generally poor. Histiocytic lymphoma was associated with widespread parenchymatous infiltration, whereas PDLL was usually associated with leptomeningeal seeding. The clinical course and the neuropathologic findings are discussed.Cancer 36:225-231, 1975.

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Involvement of the nervous system in malignant lymphoma in Nigeria.

Abstract: Images Fig. 11 Fig. 12 Fig. 13 Fig. 14 Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 Fig. 10

Cited by 29 publications

References 8 publications

Intracranial neoplasmin Ibadan, Nigeria

Intracranial neoplasmin Ibadan, Nigeria

Die Meningosis neoplastica und ihre Prophylaxe bei malignen Non-Hodgkin-Lymphomen

Involvement of the central nervous system in non-hodgkin's lymphoma

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