Involvement of the central nervous system in patient with chronic inflammatory demyelinating polyneuropathy: a case report

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an uncommon disease characterized by heterogeneous clinical findings, absence of specific laboratory markers and good response to treatment. Typically CIDP manifests as weakness of varying severity, from minimal paresis to plegia, as well as symmetrical loss of sensitivity in all limbs, a distinctive clinical feature of CDL is the involvement of both proximal and distal parts of extremities. At the same time, there is a large number of atypical CIDP variants, clinically similar to other chronic disimmune neuropathies. Neuroimaging findings typically include involvement of the cauda equina, brachial, and lumbar plexus. The patient sought medical help complaining of weakness and loss of sensation in the extremities. This clinical case illustrates a combined involvement of cranial and spinal nerves, as well as spinal cord and brain in a patient with chronic inflammatory demyelinating polyneuropathy.