Involvement of ribosomal protein RPL27a in meristem activity and organ development

Szakonyi, Dóra; Byrne, Mary E.

doi:10.4161/psb.6.5.15070

Cited by 16 publications

(11 citation statements)

References 22 publications

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“…In A. thaliana , mutations that perturb ribosomal function lead to a broad spectrum of leaf abnormalities, including smaller, narrower and pointier leaves with fewer trichomes (Byrne, ; Szakonyi and Byrne, , ). These defects have been interpreted as general growth and differentiation defects, consistent with what is reported here for sil3 and also with results reported for virus‐induced silencing of RLI genes in Nicotiana (Petersen et al ., ).…”

Section: Discussionmentioning

confidence: 99%

SIMPLE LEAF3 encodes a ribosome‐associated protein required for leaflet development in Cardamine hirsuta

et al. 2012

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SUMMARYLeaves show considerable variation in shape, and may be described as simple, when the leaf is entire, or dissected, when the leaf is divided into individual leaflets. Here, we report that the SIMPLE LEAF3 (SIL3) gene is a novel determinant of leaf shape in Cardamine hirsuta -a dissected-leaved relative of the simpleleaved model species Arabidopsis thaliana. We show that SIL3 is required for leaf growth and leaflet formation but leaf initiation is less sensitive to perturbation of SIL3 activity. SIL3 is further required for KNOX (knotted1-like homeobox) gene expression and localized auxin activity maxima, both of which are known to promote leaflet formation. We cloned SIL3 and showed that it encodes RLI2 (RNase L inhibitor 2), an ATP binding cassette-type ATPase with important roles in ribosome recycling and translation termination that are conserved in eukaryotes and archaea. RLI mutants have not been described in plants to date, and this paper highlights the potential of genetic studies in C. hirsuta to uncover novel gene functions. Our data indicate that leaflet development is sensitive to perturbation of RLI2-dependent aspects of cellular growth, and link ribosome function with dissected-leaf development.

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Section: Discussionmentioning

confidence: 99%

SIMPLE LEAF3 encodes a ribosome‐associated protein required for leaflet development in Cardamine hirsuta

et al. 2012

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“…Cite this article as Cold Spring Harb Perspect Biol 2015;7:a019190 terning, have been described in ribosomal-protein mutants (Nishimura et al 2005;Szakonyi and Byrne 2011). The question how genes with housekeeping functions can influence growth in such a specific way is addressed in a current review by Tsukaya et al (2013).…”

Section: Size Control In Plantsmentioning

confidence: 99%

Size Control in Plants—Lessons from Leaves and Flowers

Czesnick

Lenhard

2015

Cold Spring Harb Perspect Biol

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To achieve optimal functionality, plant organs like leaves and petals have to grow to a certain size. Beginning with a limited number of undifferentiated cells, the final size of an organ is attained by a complex interplay of cell proliferation and subsequent cell expansion. Regulatory mechanisms that integrate intrinsic growth signals and environmental cues are required to enable optimal leaf and flower development. This review focuses on plantspecific principles of growth reaching from the cellular to the organ level. The currently known genetic pathways underlying these principles are summarized and network connections are highlighted. Putative non -cell autonomously acting mechanisms that might coordinate plant-cell growth are discussed.

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“…Other rRNA processing--related factors with roles in embryogenesis show different expression patterns, suggesting unique roles during other stages of plant growth [38]. The ribosomal protein RPL27a plays role in meristem activity and organ development [56]. The Arabidopsis protein arginine methyltransferase 3, whose role could be typically linked to DNA transcription or mRNA splicing, has also been found to regulate ribosome biogenesis [57].…”

Section: Discussionmentioning

confidence: 99%

Analysis of Block of cell proliferation 1 (BOP1) activity in strawberry and Arabidopsis

et al. 2016

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Block of cell proliferation (BOP) proteins are conserved among eukaryotes, and studies in mammals and yeast have described their role in ribosome biogenesis and cell cycle regulation. A BOP1 orthologue was identified in plants, and loss-of-function analyses in tobacco cells confirmed similar activities. This report characterizes a role for BOP1 activity in planta. Two transgenic plant species were used: the diploid strawberry (Fragaria vesca) and Arabidopsis thaliana. FvBOP1 silencing showed changes in pre-rRNA processing, and demonstrated FvBOP1's role in growth and physiology throughout different stages of plant development. In the strawberry, repression of FvBOP1 activity decreased plant fitness prior to flowering, followed by plant death after the reproductive transition, indicating that BOP1 activity is required for transition back to vegetative growth after flowering. A T-DNA null allele of the AtBOP1 gene is lethal, and a 50% decrease in transcript accumulation is sufficient to cause severe developmental defects linked to defective cell division. The conserved protein BOP1 is essential for viability. Lower transcript levels result in defects in rRNA processing and developmental abnormalities that are consistent with its predicted role in ribosome biogenesis.

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Involvement of ribosomal protein RPL27a in meristem activity and organ development

Cited by 16 publications

References 22 publications

SIMPLE LEAF3 encodes a ribosome‐associated protein required for leaflet development in Cardamine hirsuta

SIMPLE LEAF3 encodes a ribosome‐associated protein required for leaflet development in Cardamine hirsuta

Size Control in Plants—Lessons from Leaves and Flowers

Analysis of Block of cell proliferation 1 (BOP1) activity in strawberry and Arabidopsis

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