Involvement of inflammation in the medial temporal region in the development of agitation in Alzheimer's disease: an in vivo positron emission tomography study
Abstract:Background
The evaluation of 11C‐DPA‐713 binding using positron emission tomography for quantifying the translocator protein can be a sensitive approach in determining the level of glial activation induced by neuroinflammation. Herein, we aimed to investigate the relationship between regional 11C‐DPA713‐binding potential (BPND) and neuropsychiatric symptoms (NPS) in amyloid‐positive Alzheimer's disease (AD) patients.
Methods
Fifteen AD patients were enrolled in this study. Correlations were evaluated between t… Show more
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