Involvement of immune response in anti-tumor effects of Staphylococcus Aureus Filtrate Preparation

Zhang, Bo; Fang, Yuanjian; Cao, Ji; Zhang, Chong; Ying, Meidan; He, Qiaojun; Yang, Bo

doi:10.1007/s00432-007-0293-y

Cited by 3 publications

(2 citation statements)

References 17 publications

(17 reference statements)

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“…In vivo anticancer activity was evaluated against H 22 -bearing kunmin mice, as previously described by [4]. Mice were inoculated subcutaneously into the right anterior axillary with H 22 cells (0.2 ml each).…”

Section: Modeling and Animal Groupsmentioning

confidence: 99%

Notice of Retraction: The Inhibition of Tupistra chinensis Baker Extracts on Mice H22 Hepatocarcinoma Xenograft

Huang

2011

2011 5th International Conference on Bioinformatics and Biomedical Engineering

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Tupistra chinensis Baker is a widely used medicinal plant in western area of China. In this study, we investigated the effect of Tupistra chinensis Baker extracts on mice H 22 hepatocarcinoma xenograft. The mice H 22 hepatocarcinoma xenograft animal model was made up firstly. And the mice were administrated by gavage with different concentrations of Tupistra chinensis Baker extracts for 15 days, and the xenograft growth condition, histological study and electron microscopy were used. Compared to model, Tupistra chinensis Baker extracts could significantly inhibit the xenograft growth. Big mass necroses were observed under the light microscope. Further electron microscope observation found that cancer cells apoptosis was severe. Our animal experiments demonstrated that Tupistra chinensis Baker extracts can inhibit the growth of H 22 hepatocarcinoma xenograft probably through apoptosis.

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Section: Modeling and Animal Groupsmentioning

confidence: 99%

Notice of Retraction: The Inhibition of Tupistra chinensis Baker Extracts on Mice H22 Hepatocarcinoma Xenograft

Huang

2011

2011 5th International Conference on Bioinformatics and Biomedical Engineering

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“…Anticancer activity in vivo was evaluated against H 22bearing Kunmin mice, as previously described [5]. Mice were inoculated subcutaneously into the right anterior axillary with H 22 cells (0.2 mL each).…”

Section: Modeling and Animal Groupsmentioning

confidence: 99%

Anticancer Effect of Plant-Derived Polysaccharides on Mice

Huang¹

2013

JCT

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Tupistra chinensis is a widely used medicinal plant in Hubei Province,China. In our study, we investigated the effect of polysaccharides component from Tupistra chinensis on mice in vivo. The mice H₂₂ hepatocarcinoma animal model was established firstly. Then, the mice were fed with different doses of polysaccharides derived from Tupistra chinensis (one time each day). The neoplasm growth condition was analyzed and histological and electron microscopic analyses were performed. Compared to the control, Tupistra chinensis significantly inhibited the neoplasm growth. Large mass necrosis in the mouse model was observed under the light microscope and the necrosis area was significantly increased in the Tupistra chinensis-treated mice. Electron microscopic observations showed that severe apoptosis occurred in the cancer tissue in the mouse model and apoptosis was also significantly increased in Tupistra chinensis-treated mice. Our study demonstrated that Tupistra chinensis could inhibit the growth of H₂₂ hepatocarcinoma. The mechanisms could involve the inhibitory effects of Tupistra chinensis on apoptosis, although the precise mechanisms remained to be elucidated in future study.

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The Role of Staphylococcal Protein A (SPA) in the Virulence of Staphylococcus aureus Infections.

Khateb¹

2014

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Involvement of immune response in anti-tumor effects of Staphylococcus Aureus Filtrate Preparation

Abstract: SAFP exhibited high efficiency in inhibiting the growth of cancer cells in a dose-dependent manner, which possibly attributed to its regulatory effects of immune system.

Cited by 3 publications

References 17 publications

Notice of Retraction: The Inhibition of Tupistra chinensis Baker Extracts on Mice H22 Hepatocarcinoma Xenograft

Notice of Retraction: The Inhibition of Tupistra chinensis Baker Extracts on Mice H22 Hepatocarcinoma Xenograft

Anticancer Effect of Plant-Derived Polysaccharides on Mice

The Role of Staphylococcal Protein A (SPA) in the Virulence of Staphylococcus aureus Infections.

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