Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae)

Souza, Priscila de; Crestani, Sandra; Silva, Rita de Cássia Vilhena da; Gasparotto, Francielli; Kassuya, Cândida Aparecida Leite; Silva-Santos, José Eduardo da; Gasparotto, Arquimedes

doi:10.1016/j.jep.2013.06.015

Cited by 31 publications

(17 citation statements)

References 15 publications

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“…Multiple reports are consistent with the notion that renal KKS promotes diuresis and natriuresis largely due to inhibition of tubular reabsorption of water and sodium (de Souza et al, 2013;Mukai, Fitzgibbon, Bozeman, Margolius, & Ploth, 1996;Rhaleb, Yang, & Carretero, 2011;Siragy, 1993;Sivritas et al, 2008;Suzuki, Katori, Fujita, Kumagai, & Majima, 2000). It appears that these effects occur in the absence of changes in glomerular filtration rate and renal blood flow (Siragy, 1993;Sivritas et al, 2008).…”

Section: Regulation Of Distal Nephron Sodium Reabsorption By Bk: a Rosupporting

confidence: 59%

Control of ENaC-Mediated Sodium Reabsorption in the Distal Nephron by Bradykinin

Mamenko

Zaika

Boukelmoune

et al. 2015

Hormones and Transport Systems

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Section: Regulation Of Distal Nephron Sodium Reabsorption By Bk: a Rosupporting

confidence: 59%

Control of ENaC-Mediated Sodium Reabsorption in the Distal Nephron by Bradykinin

Mamenko

Zaika

Boukelmoune

et al. 2015

Hormones and Transport Systems

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“…This experimental set followed the method previously described by Gasparotto Junior et al . and de Souza et al . Briefly, after the animals have received the overload of saline solution, the normotensive rats were orally treated with acetylcholine muscarinic receptor antagonist (atropine; 1.5 mg/kg), cyclooxygenase inhibitor (indomethacin; 5 mg/kg), nitric oxide synthase inhibitor ( l ‐NAME; 60 mg/kg) or just vehicle (1 ml/kg).…”

Section: Methodsmentioning

confidence: 99%

Chemical composition and diuretic, natriuretic and kaliuretic effects of extracts ofMimosa bimucronata(DC.) Kuntze leaves and its majority constituent methyl gallate in rats

Schlickmann

Souza

Boeing

et al. 2017

Journal of Pharmacy and Pharmacology

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“…The seeds of Gundelia tournefortti L. (Asteraceae) are often used as pickles, and it is an effective diuretic (Çoruh et al, 2007). Achillea millefolium L., which is a plant species from the Asteraceae plant family, also exhibited diuretics effect in a hypertension group (De Souza et al, 2013). It is often found in Brazil and used as the Brazilian folk medicine, usually for kidney and heart diseases.…”

Section: Introductionmentioning

confidence: 99%

A Review on the Potential Use of Medicinal Plants From Asteraceae and Lamiaceae Plant Family in Cardiovascular Diseases

2020

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Cardiovascular diseases are one of the most prevalent diseases worldwide, and its rate of mortality is rising annually. In accordance with the current condition, studies on medicinal plants upon their activity on cardiovascular diseases are often being encouraged to be used in cardiovascular disease management, due to the availability of medicinal values in certain dedicated plants. This review was conducted based on two plant families, which are Asteraceae and Lamiaceae, to study on their action in cardiovascular disease relieving activities, to review the relationship between the phytochemistry of Asteraceae and Lamiaceae families and their effect on cardiovascular diseases, and to study their toxicology. The medicinal plants from these plant family groups are collected based on their effects on the mechanisms that affect the cardiovascular-related disease which are an antioxidant activity, anti-hyperlipidemic or hypocholesterolemia, vasorelaxant effect, antithrombotic action, and diuresis effect. In reference to various studies, the journals that conducted in vivo or in vitro experiments, which were used to prove the specific mechanisms, are included in this review. This is to ensure that the scientific value and the phytochemicals of the involved plants can be seen based on their activity. As a result, various plant species from both Asteraceae and Lamiaceae plant family have been identified and collected based on their study that has proven their effectiveness and uses in cardiovascular diseases. Most of the plants have an antioxidant effect, followed by anti-hyperlipidemia, vasorelaxant, antithrombotic, and diuretic effect from the most available to least available studies, respectively. These are the mechanisms that contribute to various cardiovascular diseases, such as heart attack, stroke, coronary heart disease, and hypertension. Further studies can be conducted on these plant species by identifying their ability and capability to be developed into a new drug or to be used as a medicinal plant in treating various cardiovascular diseases.

show abstract

Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae)

Cited by 31 publications

References 15 publications

Control of ENaC-Mediated Sodium Reabsorption in the Distal Nephron by Bradykinin

Control of ENaC-Mediated Sodium Reabsorption in the Distal Nephron by Bradykinin

Chemical composition and diuretic, natriuretic and kaliuretic effects of extracts ofMimosa bimucronata(DC.) Kuntze leaves and its majority constituent methyl gallate in rats

A Review on the Potential Use of Medicinal Plants From Asteraceae and Lamiaceae Plant Family in Cardiovascular Diseases

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