[INVITED] Recent advances in surface plasmon resonance based fiber optic chemical and biosensors utilizing bulk and nanostructures

Gupta, Banshi D.; Kant, Ravi

doi:10.1016/j.optlastec.2017.11.015

Cited by 182 publications

(87 citation statements)

References 115 publications

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“…We argue that the LDF sensor has a higher sensitivity compared to the HCS due to a higher number of modes internally excited by the Several comparative analyses between different fiber-optic-based SPR sensor configurations (D-shaped fibers, tapered fibers, single-mode fibers, U-shaped fibers, TFBGs fibers, heterocore fibers, etc.) can be found in excellent review papers [4,5,24]. Here, we just compare the performance of our sensor with those of a similar SPR sensor configuration based on an HCS optical fiber (FT300EMT from Thorlabs) [19].…”

Section: Resultsmentioning

confidence: 99%

Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers

et al. 2018

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Abstract:In this paper, we show that light-diffusing fibers (LDF) can be efficiently used as host material for surface plasmon resonance (SPR)-based refractive index sensing. This novel platform does not require a chemical procedure to remove the cladding or enhance the evanescent field, which is expected to give better reproducibility of the sensing interface. The SPR sensor has been realized by first removing the cladding with a simple mechanical stripper, and then covering the unclad fiber surface with a thin gold film. The tests have been carried out using water-glycerin mixtures with refractive indices ranging from 1.332 to 1.394. The experimental results reveal a high sensitivity of the SPR wavelength to the outer medium's refractive index, with values ranging from 1500 to~4000 nm/RIU in the analyzed range. The results suggest that the proposed optical fiber sensor platform could be used in biochemical applications.

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Section: Resultsmentioning

confidence: 99%

Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers

et al. 2018

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“…The light scatters from a topological defect on the surface of the metallic particles or nanostructures [38,39]. In contrast with the SPPs, in which the coupling occurs at the surface of the metal layer, the collective oscillations of the free electron cloud in LSPPs are confined in metal nanoparticles or nanostructures [40].…”

Section: Localized Surface Plasmon Polaritonsmentioning

confidence: 99%

“…Schematic illustration of surface plasmons propagating at the interface between metal nanoparticle and dielectric materials[40].…”

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confidence: 99%

Recent Advances in Plasmonic Sensor-Based Fiber Optic Probes for Biological Applications

et al. 2019

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The survey focuses on the most significant contributions in the field of fiber optic plasmonic sensors (FOPS) in recent years. FOPSs are plasmonic sensor-based fiber optic probes that use an optical field to measure the biological agents. Owing to their high sensitivity, high resolution, and low cost, FOPS turn out to be potential alternatives to conventional biological fiber optic sensors. FOPS use optical transduction mechanisms to enhance sensitivity and resolution. The optical transduction mechanisms of FOPS with different geometrical structures and the photonic properties of the geometries are discussed in detail. The studies of optical properties with a combination of suitable materials for testing the biosamples allow for diagnosing diseases in the medical field.

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“…Biomolecular optical fiber sensing is based on different processing methods, frequently relying on the interaction of the evanescent field with the external medium. Indeed, as label free detection can be source of significant advances to produce tools for rapid medical diagnosis, a great number of approaches based on surface plasmon resonance (SPR) phenomenon have been developed [15][16][17][18][19][20][21]. Several strategies exist to enable the evanescent field to reach the sensed medium: cladding removed evanescent wave, and tapered or fiber Bragg grating configurations were mainly described.…”

Section: Introductionmentioning

confidence: 99%

Multiplexed Remote SPR Detection of Biological Interactions through Optical Fiber Bundles

Desmet

Vindas

Meza

et al. 2020

Sensors

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The development of sensitive methods for in situ detection of biomarkers is a real challenge to bring medical diagnosis a step forward. The proof-of-concept of a remote multiplexed biomolecular interaction detection through a plasmonic optical fiber bundle is demonstrated here. The strategy relies on a fiber optic biosensor designed from a 300 µm diameter bundle composed of 6000 individual optical fibers. When appropriately etched and metallized, each optical fiber exhibits specific plasmonic properties. The surface plasmon resonance phenomenon occurring at the surface of each fiber enables to measure biomolecular interactions, through the changes of the retro-reflected light intensity due to light/plasmon coupling variations. The functionalization of the microstructured bundle by multiple protein probes was performed using new polymeric 3D-printed microcantilevers. Such soft cantilevers allow for immobilizing the probes in micro spots, without damaging the optical microstructures nor the gold layer. We show here the potential of this device to perform the multiplexed detection of two different antibodies with limits of detection down to a few tenths of nanomoles per liter. This tool, adapted for multiparametric, real-time, and label free monitoring is minimally invasive and could then provide a useful platform for in vivo targeted molecular analysis.

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[INVITED] Recent advances in surface plasmon resonance based fiber optic chemical and biosensors utilizing bulk and nanostructures

Cited by 182 publications

References 115 publications

Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers

Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers

Recent Advances in Plasmonic Sensor-Based Fiber Optic Probes for Biological Applications

Multiplexed Remote SPR Detection of Biological Interactions through Optical Fiber Bundles

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