Investigations on the effect of a niacin supplementation to three diets differing in forage-to-concentrate ratio on several blood and milk variables of dairy cows

Niehoff, Inka-Donata; Hüther, Liane; Lebzien, Peter; Bigalke, Wiebke; Dänicke, Sven; Flachowsky, Gerhard

doi:10.1080/17450390902863764

Cited by 15 publications

(18 citation statements)

References 34 publications

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“…In the present trial, NA was below detection limit. High blood NAM concentrations are usually the result of a high level of concentrate in the diet combined with niacin (Niehoff et al, 2009b), but in the present study the highest NAM plasma concentration was found in Group 30 + NA. In agreement with Driver et al (1990), Ottou et al (1995) and Cervantes et al (1996), an increase was found in plasma NAM concentration after niacin supplementation.…”

Section: Discussionmentioning

confidence: 44%

“…The mechanism that leads to the disappearance of supplemental niacin is not known. Moreover, Niehoff et al (2013) concluded that synthesis of niacin is lower in rations containing a high proportion of forage, so the high plasma niacin content of Group 30 + NA in the present study is probably because of the supplemental niacin. There is lack of understanding of the effects of feeding on niacin degradation and synthesis.…”

Section: Discussionmentioning

confidence: 78%

“…Mechanisms such as degradation and degradation by microflora that is greater than synthesis are not known (Niehoff et al, 2009a). In addition, niacin synthesis did not seem to occur if NA or NAM was supplemented (Hannah & Stern, 1985;Niehoff et al, 2013). Santschi et al (2005a) stated that diets with higher amounts of concentrate affected ruminal vitamin synthesis, and substantial losses occurred.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, higher niacin degradation in Group 60 + NA than in Group 30 + NA might have occurred owing to the high level of concentrate, which might negatively influence the ruminal environment, and thus rumen microbes, and accordingly decreases in ruminal production. Niehoff et al (2013) indicated that degradation in the rumen or absorption before the duodenal cannula may take place. The mechanism that leads to the disappearance of supplemental niacin is not known.…”

Section: Discussionmentioning

confidence: 99%

“…RB 1008, Randox Laboratories GmbH, Krefeld). Niacin concentration in plasma was determined with high performance liquid chromatography (HPLC), as described by Niehoff et al (2009b).…”

Section: Methodsmentioning

confidence: 99%

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Effects of niacin supplementation (40 weeks) and two dietary levels of concentrate on performance, blood and fatty acid profiles of dairy cattle

Rauls¹,

Meyer²,

Hüther³

et al. 2015

SA J. An. Sci.

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The present study was conducted to investigate the effects of 24 g niacin (nicotinic acid (NA)) supplementation over 40 weeks with two forage-to-concentrate ratios (60% concentrate vs. 30% in the total diet) on performance variables of energy metabolism such as plasma concentrations of non-esterified fatty acids (NEFA), beta-hydroxybutyrate (BHB), glucose and nicotinamide (NAM), and the fatty acid profile in rumen fluid. In a 2 x 2 factorial design, 64 German Holstein cows were divided postpartum into four dietary groups: i) 60% concentrate supplemented with 24 g NA (Group 60 + NA); ii) 60% concentrate without NA (Group 60−); iii) 30% concentrate with 24 g NA (Group 30 + NA) and iv) 30% concentrate without NA (Group 30−). The experiment started on the day of calving and continued for 40 weeks. Niacin supplementation did not affect milk yield or composition. The plasma niacin content increased in the supplemented groups, especially Group 30 + NA. Niacin supplementation led to decreased plasma glucose concentrations. The interaction of concentrate x niacin enhanced the molar proportion of propionic acid in rumen fluid in Group 60 + NA. Total short-chain fatty acid (SCFA) concentrations were increased by level of concentrate, niacin supplementation and the interaction, concentrate x niacin. Plasma levels of NEFA and BHB remained unaffected. In sum, concentrate level, niacin supplementation and the interaction of concentrate x niacin increased plasma NAM concentration, whereas plasma glucose concentration was decreased by niacin supplementation. ______________________________________________________________________________________

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Section: Discussionmentioning

confidence: 44%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…RB 1008, Randox Laboratories GmbH, Krefeld). Niacin concentration in plasma was determined with high performance liquid chromatography (HPLC), as described by Niehoff et al (2009b).…”

Section: Methodsmentioning

confidence: 99%

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