Investigations of Molluscicidal Activity of Certain Sudanese Plants Used in Folk-Medicine. Part IV*

Hadi, A.; Bashir, A. K.; Kheir, Y. M. El

doi:10.1055/s-2007-969625

Cited by 23 publications

(3 citation statements)

References 4 publications

(5 reference statements)

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“…obs.). Saponin compounds may also be present, as indicated by the persistent foam formed during extract preparation, and these are known to cause haemolysis in molluscs and other animals (El Hadi et al , 1984;Farnsworth et al , 1987). The degree of haemorrhaging, which appeared to be proportional to the extract concentration of Ap.…”

Section: Discussionmentioning

confidence: 99%

The molluscicidal properties of Apodytes dimidiata (Icacinaceae): geographical variation in molluscicidal potency

Td¹

1999

Annals of Tropical Medicine And Parasitology

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Synthetic molluscicides have proved too expensive for most countries wanting to include snail control in their anti-schistosomiasis programmes. An alternative, which is not only cheaper but also promotes self-reliance and empowerment of the affected communities, is the use of molluscicidal plants. An often-cited limitation to using such natural products is the geographical variation in the toxicity of candidate species. The geographical variation in the molluscicidal activity of Apodytes dimidiata was investigated in South Africa. Leaves of this plant were collected from six, widely separate localities within the areas of the country where schistosomiasis is endemic. The results of bio-assays using the intermediate host snail, Bulinus africanus, clearly showed that variation in toxicity did exist and appeared to be correlated with the range in mean annual temperatures and altitude where the plants grew. Whether the variation was a phenoplastic response to the environment or genetically determined still has to be investigated. Nevertheless, a thorough knowledge of the geographical variation in the level of the active compound(s) in the candidate plants in endemic areas will be needed prior to the implementation of plant-propagation and snail-control programmes.

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Section: Discussionmentioning

confidence: 99%

The molluscicidal properties of Apodytes dimidiata (Icacinaceae): geographical variation in molluscicidal potency

Td¹

1999

Annals of Tropical Medicine And Parasitology

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“…The solvents used include water (natural, synthetic, distilled, dechlorinated and/or boiled; Archibald, 1933;Ritchie et al, 1963;Evans et al, 1986;Alard et al, 1991;Lwambo and Moyo, 1991;Monkiedje et al, 1991;Ferrer Lopez et al, 1993;Yong and Rodriguez, 1994;Brackenbury and Appleton, 1997a, b), butanol (Spielman and Lemma, 1973;Lemma and Yau, 1974a), petroleum ether and dichlorom ethane (El Hadi et al, 1984;Appleton et al, 1992), hexane (Pereira et al, 1978), methanol (Silva and Rouquayrol, 1971;Alard et al, 1991), ethanol Shabana et al, 1988) and aqueous carboxym ethyl cellulose (Alard et al, 1991), amongst others. Most of the extraction procedures have involved the specialized use of expensive chem icals and equipment.…”

Section: Preparation Of the Crude Aqueous Plant Extractmentioning

confidence: 99%

Proposed standardization of assessment protocols for plant molluscicides for use in self help control programmes

Td¹

1998

Annals of Tropical Medicine And Parasitology

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Several candidate plant molluscicides have been identified for possible incorporation into self-help control programmes against schistosomiasis, but their full potential has yet to be realised. This has been, in the most part, due to the absence of standardized assessment and toxicity protocols, and subsequently the inability to register crude plant products in their country of origin or internationally. In an attempt to solve this dilemma, a series of protocols has been designed which will provide a useful standardized guideline for investigations into plant molluscicides, as well as precipitate moves towards the establishment of internationally accepted guidelines for the assessment of various categories of plant biopesticides. Ultimately, being able to register a crude plant extract will permit health organizations such as the World Health Organization to promote the use of such material, especially in self-help control programmes, thereby improving the health standards of rural communities.

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“…Recently, the molluscicidal activity of P. erioptera DC. has been reported (4). The search for new biologically-active compounds from plants of this genus led to the investigation of P. paniculata L., collected in Panama.…”

Section: Introductionmentioning

confidence: 99%

Coumarins fromPolygala paniculata

1985

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From the petrol ether and chloroform extracts of Polygala paniculata L. (Polygalaceae), possessing both molluscicidal and antifungal properties, four coumarins were isolated by flash chromatography and centrifugal thin-layer chromatography. They were identified as aurapten, phebalosin, murrangatin and 7-methoxy-8-(1 ,4-dihydroxy-3-methyl-2-butenyl)coumarin, a new natural product.Among these compounds phebalosin showed biological activity, but proved to be very unstable in aqueous solution.

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Investigations of Molluscicidal Activity of Certain Sudanese Plants Used in Folk-Medicine. Part IV*

Cited by 23 publications

References 4 publications

The molluscicidal properties of Apodytes dimidiata (Icacinaceae): geographical variation in molluscicidal potency

The molluscicidal properties of Apodytes dimidiata (Icacinaceae): geographical variation in molluscicidal potency

Proposed standardization of assessment protocols for plant molluscicides for use in self help control programmes

Coumarins fromPolygala paniculata

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