Investigations of efficacy of intramammary applied antimicrobials and glucocorticosteroides in the treatment of subclinical and clinical mastitis in cows

Abstract

Inflammation of the mammary gland, mastitis in cows, presents one of the most acute problems in intensive dairy production, inflicting huge economic losses. In the course of one year, 80 samples were taken at investigated farms from udder quarters of cows with clinical mastitis and 160 samples from udder quarters of cows with subclinical mastitis. The efficacy of three preparations, A, B, and C, was examined in the treatment of clinical and subclinical mastitis in cows. The investigations indicate that antibiotic preparation A (neomycin, polimixine B, oleandomycin and prednisolone) exhibited a greater efficacy in the treatment of clinical mastitis caused by Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis and Micrococcus sp., but a smaller efficacy in the treatment of subclinical mastitis caused by Staphylococcus aureus. Preparation B (amoxicillin, clavulanic acid and prednisolone) exhibited a higher efficacy in the treatment of clinical mastitis caused by Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis and Micrococcus, but a weaker effect in the treatment of subclinical mastitis caused by Staphylococcus aureus. Preparation C (procaine penicillin G, streptomycin, neomycin sulfate and prednisolone acetate) exihibited efficacy in the treatment of clinical and subclinical mastitis caused by Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, Micrococcus, Staphylococcus aureus and Esherichie coli. [Projekat Ministarstva nauke Republike Srbije, br. III 46002: Molekularno-genetička i ekofiziološka istraživanja u zaštiti autohtonih animalnih genetičkih resursa, očuvanju dobrobiti, zdravlja i reprodukcije gajenih životinja i proizvodnji bezbedne hrane

New Perspective of Origanum vulgare L. and Satureja montana L. Essential Oils as Bovine Mastitis Treatment Alternatives

“…Antibiotics included in the antibiotic susceptibility testing were amoxycillin, ampicillin, ceftriaxone, enrofloxacin, erythromycin, lincomycin, neomycin, penicillin, streptomycin, tetracycline, amoxicillin/clavulanic acid, novobiocin, trimethoprim/sulfamethoxazole, and cloxacillin. The current data suggests that the most commonly used antibiotics in mastitis therapy in Serbia are penicillin, streptomycin, gentamicin, tetracycline, cephalexin, sulfonamides, and enrofloxacin [ 21 , 22 , 23 ]. According to the data obtained in this study, all mastitis associated pathogens are resistant to penicillin, which is not surprising, considering the previously stated fact.…”

Environmental Bovine Mastitis Pathogens: Prevalence, Antimicrobial Susceptibility, and Sensitivity to Thymus vulgaris L., Thymus serpyllum L., and Origanum vulgare L. Essential Oils

“…Antimicrobials are an important part of mastitis therapy [ 40 , 46 , 47 ]. Determination of the antimicrobial susceptibility pattern is necessary to choose the appropriate antimicrobial treatment for cows [ 48 ].…”

Farm Animal Veterinarians’ Knowledge and Attitudes toward Antimicrobial Resistance and Antimicrobial Use in the Republic of Serbia

“…The improvement of biosecurity should be a general measure for prevention of mastitis prevalence; however, currently, antimicrobial treatment remains the main solution to improve animal health and welfare [ 77 ], whereby antibiotics are mostly given without the identification of the causative pathogen [ 78 ]. Previous research suggests that the most commonly used antibiotics in mastitis therapy in Serbia were penicillin, streptomycin, gentamicin, tetracycline, cephalexin, sulfonamides, and enrofloxacin [ 79 , 80 ]. Furthermore, according to recent data [ 81 , 82 ], the most common mastitis pathogens in dairy cows from Serbia were resistant to penicillin.…”