Investigations into the specific effects of rosemary oil at the receptor level

Sagorchev, P.; Lukanov, J; Am, Beer

doi:10.1016/j.phymed.2009.09.012

Cited by 19 publications

(8 citation statements)

References 6 publications

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“…[ 24 ] Some other Bulgarian researchers used Rosmarinus as a muscle relaxer and antagonist of alpha 1 and 2 adrenergic receptors and obtained positive results. [ 25 ] Mexican researchers studied the spasmolytic effect of Rosmarinus on the muscles and its effect on calcium channels, and also tested its ethanol essence on Guinea pigs’ ileum and obtained results consistent with the present study. [ 14 ] Orally infused Rosmarinus was used in the present study, which is a popular and simple method in Iran.…”

Section: Discussionsupporting

confidence: 87%

The effect of Rosmarinus herbal tea on occupational burnout in Iran Chemical Industry Investment company employees

Mehrabi

Gorji

Zolfaghari

et al. 2015

Iranian J Nursing Midwifery Res

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Background:Burnout is one of the most important problems that the employees encounter. Many health problems arise due to burnout which is to be dealt with by the employees and the owners in the industry. Among many different ways of dealing with this problem, herbal therapy seems to be a promising solution. The present study intended to investigate the effect of Rosmarinus officinalis (RO) on burnout in employees who work in industrial environments.Materials and Methods:An experimental study was performed to see whether RO has an effect on burnout or not. A total of 66 employees, aged between 20 and 60 years, who had worked for at least 1 year in the technical wards of Iran Chemical Industry Investment Company took part in the study. The participants were randomly assigned to two groups of control (n = 33) and RO (n = 33). The RO group received 4 g of Rosemary in 150 cc water per day for 2 months. The control group, on the other hand, did not receive anything. The data were collected via Geldard (1989) Burnout Inventory before and after the treatment. A t-test was performed to analyze the collected data.Results:The results of statistical tests showed that after intervention, the score of occupational burnout in RO group was better, and a significant difference was found between the control and experimental groups (P = 0.03), in favor of the experimental group.Conclusions:The results of the study revealed that Rosmarinus had a positive effect on burnout in employees in this study. Further studies in this field are suggested.

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Section: Discussionsupporting

confidence: 87%

The effect of Rosmarinus herbal tea on occupational burnout in Iran Chemical Industry Investment company employees

Mehrabi

Gorji

Zolfaghari

et al. 2015

Iranian J Nursing Midwifery Res

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“…It has been shown to enhance the resistance of rat hepatocytes against DNA-damaging oxidative agents, 9 even in testicular cells. 10 It is also known that rosemary improves local blood circulation, relieves pain, 11 has anticancer activity, 12 and controls blood lipid and antilipid peroxidation, 13 among many other activities.…”

Section: ■ Introductionmentioning

confidence: 99%

Relevance of Carnosic Acid, Carnosol, and Rosmarinic Acid Concentrations in the in Vitro Antioxidant and Antimicrobial Activities of Rosmarinus officinalis (L.) Methanolic Extracts

Jordán

Lax

Rota

et al. 2012

J. Agric. Food Chem.

120

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The importance of the diterpenic and rosmarinic acid content in the biological activities of rosemary extracts has been studied previously, but how the relationship between the concentration of these components affects their antioxidant and antibacterial activities has received little attention. Accordingly, from a total of 150 plants, 27 methanolic extracts were selected, for their similar diterpene contents but different ratios between carnosic acid and carnosol concentrations. In extracts with similar rosmarinic acid contents but differing proportions between carnosic acid and carnosol, the two diterpenes were seen to equally affect the in vitro antioxidant activity; however, and related with the antibacterial efficiency, this biological activity improved when carnosol was the major diterpene component.

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“…E-mail: andre.beer@klinik-Blankenstein.de. Author(s) agree that this article remain permanently open access under the terms of the Creative Commons Attribution License 4.0 International License cineole has spasmolytic, papaverine-like effects (Sagorchev et al, 2010). It is also well known that these specific effects usually appear at much lower concentration levels.…”

Section: Introductionmentioning

confidence: 85%

Effects of 1.8-cineole (eucalyptol) on the spontaneous contractile activity of smooth muscles fibre

Plamen¹,

Lukanov²,

e-Michael³

2015

J. Med. Plants Res.

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Eucalyptus oil is frequently used in phytotherapy. The objective of the present paper was to investigate to what extent 1.8-cineole influences the activity of smooth muscle fibres. The effects of 1.8-cineole on the spontaneous contractile activity were investigated in in vitro experiments with circular smooth muscle fibres of guinea pig stomach. 1.8-cineole was found to have agonistic effects on the  1 and  2 adrenergic receptors. These effects can be registered at low concentrations of up to 3 × 10 -7 to 2 × 10 -5 M 1.8-cineole. At higher concentrations, the well-known spasmolytic effect appears. At concentrations above 4 × 10 -4 M 1.8-cineole, the effect of 10 -5 M acetylcholine is 100% suppressed. The results allow for the assumption that, besides the spasmolytic effects investigated to date and owing to its specific effects on the  2 adrenergic receptors of the nerve cells, 1.8-cineole brings about an additional improvement to local blood circulation and alleviates pain.

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Investigations into the specific effects of rosemary oil at the receptor level

Cited by 19 publications

References 6 publications

The effect of Rosmarinus herbal tea on occupational burnout in Iran Chemical Industry Investment company employees

The effect of Rosmarinus herbal tea on occupational burnout in Iran Chemical Industry Investment company employees

Relevance of Carnosic Acid, Carnosol, and Rosmarinic Acid Concentrations in the in Vitro Antioxidant and Antimicrobial Activities of Rosmarinus officinalis (L.) Methanolic Extracts

Effects of 1.8-cineole (eucalyptol) on the spontaneous contractile activity of smooth muscles fibre

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