Investigations into the Antifungal, Photocatalytic, and Physicochemical Properties of Sol-Gel-Produced Tin Dioxide Nanoparticles

Haq, Sirajul; Shahzad, Nadia; Shahzad, Muhammad; Elmnasri, Khaled; Ali, Manel Ben; Baazeem, Alaa; Hedfi, Amor; Ehsan, Rimsha

doi:10.3390/molecules27196750

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…To study the crystalline nature and other crystallographic parameters, XRD (model: Panalytical X'pert Pro) was run. The surface topology was examined through SEM (model JSM 5910) and TEM (model HITACHI H-7700), whereas the chemical composition of MOF was studied via FTIR (model Nicolet 6700) [22,23].…”

Section: Instrumentationmentioning

confidence: 99%

Nickel-L-leucine framework (MOF): synthesis, structural characterization, and potential applications in biological studies

Kiran,

Yasin,

Haq

et al. 2023

Mater. Res. Express

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The microbial resistance to antibiotics and the generation of free radicals inside as a result of different oxidative processes are modern global challenges for researchers. The exploration of MOFs as an antibacterial agent against pathogenic bacteria and as an antioxidant agent to scavenge free radicals as countermeasures to alleviate these problems. For this purpose, the metal organic framework (MOF), composed of L-leucine as a linker and nickel as a metal, was synthesized via a convenient, one-pot process under reflux conditions. The products formed were characterized through different techniques, including N2 adsorption experiments, Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The physicochemical analysis shows that the MOF has a crystalline nature with a surface area of 129 (±5) m2/g and a pore size of 1.95 nm. The synthesized MOF was then subjected to antibacterial activity, and the high activity was recorded against S. aureus. The dose-dependent antioxidant study shows the activity increases with increasing the concentration of the MOF. However, both the antibacterial and antioxidant activities were found to be less than those of the standard drugs (clindamycin and ascorbic acid).

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Section: Instrumentationmentioning

confidence: 99%

Nickel-L-leucine framework (MOF): synthesis, structural characterization, and potential applications in biological studies

Kiran,

Yasin,

Haq

et al. 2023

Mater. Res. Express

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“…Moreover, the high surface area and the strong electrostatic interaction of the drug-loaded nanocomposite with fungal cells could enhance the antifungal activity. The nanocomposite could also disrupt the fungal biofilm formation, which was a critical factor in fungal infections(Haq et al, 2022).…”

mentioning

confidence: 99%

Rocephin‐graphene oxide‐silver nanocomposites: A versatile platform for biomedical applications

Kashif,

Ahmed,

Altaf

et al. 2024

Microscopy Res & Technique

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For many years, the synthesis of graphene oxide (GO) had involved exfoliating graphite flakes, and the methods applied were expensive and time‐consuming. Thus, an attempt had been made to create an inventive, less expensive method for the synthesis of GO using unrefined, raw carbon‐containing material. Modified Hummer's method was used to prepare GO from banana peel. In addition, the metallic silver nanocomposite was also synthesized along with laoding of drug Rocephin where they interact with each other through electrostatic hydrogen bond interaction. The degree of crystallinity and the crystallite size were through x‐ray diffraction (XRD) analysis and the crystallite size of AgNPs was found to be 40.40 nm. The scanning electron microscopy (SEM) analysis shows that the morphology of the GO gradually changes with the addition of AgNPs and Rocephin. A blue shift was seen in the absorbance maxima of the raw carbon upon the conjugation of Rocephin in UV analysis. The Fourier‐transform infrared spectroscopy, and energy dispersive X‐ray (EDX) spectroscopy were used to determine the chemical composition of the samples. Furthermore, a broad biological screening of the synthesized samples had been carried out following the total reducing power (TRP), total antioxidant capacity (TAC), antibacterial, antifungal, MTT (Cytotoxicity of biologically synthesized silver nanoparticles in MDA‐MB‐231 human breast cancer cells) cell viability, brine shrimp lethality, and hemolytic protocols. Significant results were obtained, and the Rocephin‐GO‐AgNPs had depicted promising activity as compared with their counterparts.Research Highlights The GO was prepared from the raw carbon extracted from banana peels and was used as a substrate for the synthesis Graphene oxide silver nanoparticles (GO‐AgNPs) and Rocephin‐loaded graphene oxide silver nanoparticles (Rocephin‐GO‐AgNPs) The structural and compositional analysis of the nanomaterial was carried out, and they were screened for several biomedical applications. The Rocephin‐GO‐AgNPs exhibit the highest activity as compared with their counterparts.

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Exploring the Medical Applications of SnO2 Nanomaterials: Antimicrobial, Antiviral, and Anticancer Therapies

Chandrasekaran,

Kokkarachedu,

Sisubalan

et al. 2024

Nanotechnology in the Life Sciences

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Investigations into the Antifungal, Photocatalytic, and Physicochemical Properties of Sol-Gel-Produced Tin Dioxide Nanoparticles

Cited by 4 publications

References 22 publications

Nickel-L-leucine framework (MOF): synthesis, structural characterization, and potential applications in biological studies

Nickel-L-leucine framework (MOF): synthesis, structural characterization, and potential applications in biological studies

Rocephin‐graphene oxide‐silver nanocomposites: A versatile platform for biomedical applications

Exploring the Medical Applications of SnO2 Nanomaterials: Antimicrobial, Antiviral, and Anticancer Therapies

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