Investigation on the Chemical Composition and Antioxidant Capacity of Extracts from Crataegus azarolus L.: Effect of Growing Location of an Important Tunisian Medicinal Plant

Yahyaoui, Amira; Arfaoui, Moufida Oueslati; Rigane, Ghayth; Hkir, Achref; Amari, Kawther; Salem, Ridha Ben; Ammari, Youssef

doi:10.1007/s42250-019-00054-1

Cited by 18 publications

(18 citation statements)

References 23 publications

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“…Total Phenol content (TPC) was determined according to the Folin-Ciocalteu method as described before by Yahyaoui (p) Solid to liquid ratio (g/mL) 5 7.5 10 et al [14] with some modification. Briefly, 300 μL sample of extract diluted in methanol (2 mg/5 mL) were added to 1.5 mL of Folin-Ciocalteu reagent (10/100).…”

Section: Determination Of Total Phenolicsmentioning

confidence: 99%

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Optimization of Polyphenols Recovery from Schinus molle L. Peel Using Response Surface Methodology (RSM)

et al. 2020

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Factorial design and Response Surface Methodology (RSM) were used to model the recovery of polyphenols from Schinus molle L. peel (SM) by solvent extraction. Experiments carried out according to a Central Composite Design (CCD) allowed evaluation of the effects of temperature, extraction time, solvent composition and solid to liquid ratio on the yield of polyphenol. Statistical analysis showed that temperature was the most influential factor. A reduced polynomial model was developed by the stepwise regression method. The model was checked by performing validation experiments both inside and outside the factorial region. A very good agreement was observed between experimental and calculated extraction yields, thus supporting the use of the model to quantitatively describe the recovery of polyphenols from SM. Keywords Schinus molle • Polyphenols • Factorial design and response surface method Abbreviations RSM Response surface methodology SM Schinus molle CCD Central composite design DPPH 1,1-diphenyl-2-picrylhydrazyl TPC Polyphenol compounds yield GAE Gallic acid equivalent DM Plant dry matter X1 The non-coded values for temperature X2 The non-coded values for time X3 The non-coded values for solvent extraction X4 The non-coded values for solid to liquid ratio A Absorbance IC 50 Inhibition concentration at 50% (T) Factor temperature (p) Factor solid to liquid ratio (S)

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Section: Determination Of Total Phenolicsmentioning

confidence: 99%

“…Antiradical activity was evaluated using 1, 1-diphenyl-2-picrylhydrazyl free radical (DPPH) with some modifications [14,15]. Aliquots (1.5 mL) of various dilutions of (1) C = 8.9321A + 0.0102 r 2 = 0.9987…”

Section: Antiradical Activitymentioning

confidence: 99%

Optimization of Polyphenols Recovery from Schinus molle L. Peel Using Response Surface Methodology (RSM)

et al. 2020

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“…Previous studies revealed that the leaves, flowers, and fruits of C. azarolus had various biological activities including antimicrobial, antioxidant, antihyperglycemic, and antihyperlipidemic activities [15,16]. These potential health benefits are related to their high content in many natural active compounds, such as flavonoids, minerals, sugar alcohols, carotenoids, polyphenols, amino acids, and tannins [14,17].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Polysaccharides Extracted from Pulps and Seeds of Crataegus azarolus L. var. aronia: Preliminary Structure, Antioxidant, Antibacterial, α-Amylase, and Acetylcholinesterase Inhibition Properties

Rjeibi

Zaabi

Jouida

2020

Oxidative Medicine and Cellular Longevity

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Polysaccharides from the pulps (CAP) and seeds (CAS) of Crataegus azarolus L. var. aronia were extracted by hot water method. Both polysaccharides were characterized by scanning electron microscopy (SEM), Congo red test, FT-IR spectroscopy, and their antioxidant, α-amylase, antiacetylcholinesterase, and antibacterial activities were evaluated. CAP showed the highest total carbohydrate (82.35%) and uronic acid (29.39%) contents. The Congo red test revealed the lack of triple-helical conformation for both polysaccharides. The comparison of both infrared spectra indicated similar patterns with the presence of typical bands of polysaccharides. However, the microstructure of both samples indicated differences when analyzed by SEM. CAP displayed higher antioxidant, α-amylase, and acetylcholinesterase inhibitory activities. Besides, CAP showed the strongest antimicrobial effects against seven microorganisms and, notably, the Gram-positive bacteria. Overall, the results suggest that polysaccharides from C. azarolus L. var. aronia may be considered as novel sources of antioxidants and recommended as enzyme inhibitory agents in food and pharmaceutical industries.

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“…The extract was filtered through Whatman no. 4 paper and then stored at −21°C until further use (Yahyaoui et al., 2019).…”

Section: Methodsmentioning

confidence: 99%

Identification and quantification of phenolic and fatty acid profiles in Pinus halepensis mill. seeds by LC‐ESI‐MS and GC: Effect of drying methods on chemical composition

Mahdhi

Ghazghazi

Aloui

et al. 2021

Food Science & Nutrition

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This study aimed to evaluate Pinus halepensis Mill. seeds oil as well as methanolic‐aqueous extract on fatty acid and phenolic's composition as well as antioxidant activities with regard to the cones drying methods: convection and sun methods. The highest amounts of total phenols (14.63 ± 0.05 mg GAE/g DW), flavonoids (3.3 ± 0.02 mg QE/g DW), and condensed tannins (0.36 ± 0.05 mg CE/g DW) were showed in the seeds obtained by sun‐dried method. Methanolic‐aqueous seeds extracts were subjected to LC‐ESI‐MS analysis in order to identify and quantify the phenolic composition. This technique allowed us to identify eleven phenolic compounds: two phenolic acids and nine flavonoid compounds such as cirsiliol, catechin (+), luteolin, and luteolin‐7‐O‐glucoside, which were present in the two studied samples while apigenin, naringenin, and cirsilineol were only identified in the extract obtained from sun‐drying method seeds. The chemical components of the oils were analyzed using GC, and significant differences were found between the two studied seeds oil (p < .05). Furthermore, the antioxidant activities were investigated using DPPH and ABTS.+ assays. The results showed that the methanolic‐aqueous extract from seeds dried by sun method had the highest antioxidant activities (0.08 and 0.05 mg/ml, respectively). This study could provide useful information for industry to produce potentially bioactive plant extract.

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Investigation on the Chemical Composition and Antioxidant Capacity of Extracts from Crataegus azarolus L.: Effect of Growing Location of an Important Tunisian Medicinal Plant

Cited by 18 publications

References 23 publications

Optimization of Polyphenols Recovery from Schinus molle L. Peel Using Response Surface Methodology (RSM)

Optimization of Polyphenols Recovery from Schinus molle L. Peel Using Response Surface Methodology (RSM)

Characterization of Polysaccharides Extracted from Pulps and Seeds of Crataegus azarolus L. var. aronia: Preliminary Structure, Antioxidant, Antibacterial, α-Amylase, and Acetylcholinesterase Inhibition Properties

Identification and quantification of phenolic and fatty acid profiles in Pinus halepensis mill. seeds by LC‐ESI‐MS and GC: Effect of drying methods on chemical composition

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