Investigation on the Biodegradability and Antibacterial Properties of Nanohybrid Suture Based on Silver Incorporated PGA-PLGA Nanofibers

Rouhollahi, Farzaneh; Ravandi, Seyed Abdolkarim Hosseini; Alihosseini, Farzaneh; Allafchian, Alireza; Haghighat, Fatemeh

doi:10.1007/s12221-018-8316-7

Cited by 21 publications

(11 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figure 4 shows that fibers are smooth and they seem to be bimodal for pure PCL and PCL/Propolis 9–1 samples, meaning that both nano and microfiber populations are present in the structure. The introduction of propolis to the electrospinning solution resulted in a moderate decrease in fiber diameters from 0.722 μm for pure PCL to 0.611 for PCL/Propolis 8–2 .…”

Section: Resultsmentioning

confidence: 99%

“…scaffolds, and wound healing structures, electrospun materials have found diverse applications in energy and environmental technologies. [7][8][9][10] Regarding infections, the ever-increasing use of antibiotics has led to the problem of resistant strains. For example, Triclosan-resistant bacteria have become prevalent due to the increasing use of this antibacterial agent in nonmedical products such as cosmetics and professional healthcare products.…”

Section: Introductionmentioning

confidence: 99%

“…The potential to select from a wide array of polymers and therapeutic agents gives electrospinning significant versatility and scope as a route toward effective antibacterial biomaterials. In addition to diverse biomedical applications such as drug delivery, tissue regeneration, enzyme immobilization, artificial organs, medical protection, biological scaffolds, and wound healing structures, electrospun materials have found diverse applications in energy and environmental technologies 7–10 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Electrospun poly(e‐caprolactone)/propolis fiber morphology: A process optimisation study

Salimbeigi

Oliveira

McGuinness

2022

J of Applied Polymer Sci

View full text Add to dashboard Cite

This study focuses on combining the synthetic polymer poly(Ɛ-caprolactone) with the natural antibacterial propolis, and uses response surface methodology based on a three-level, four-variable Box-Behnken design, to model the dependence of fiber diameter distribution on process parameters. The effect of the concentration of the antibacterial substance, the flow rate, the voltage, and the collector distance were analyzed. The linear coefficients of the antibacterial content and flow rate, and the quadratic coefficients of the voltage, distance and flow rate as well as the interaction effect between voltage and distance were found to be statistically significant. Parameters capable of forming small diameter fibers were targeted for higher surface area to material volume ratios.The parameters predicted to produce a minimum average fiber diameter of 0.506 μm were then validated in a confirmatory experiment giving a 0.505 μm average. The model maps the impact of electrospinning parameters on the fabrication and morphology of PCL/propolis scaffolds, which have potential woundcare applications.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Electrospun poly(e‐caprolactone)/propolis fiber morphology: A process optimisation study

Salimbeigi

Oliveira

McGuinness

2022

J of Applied Polymer Sci

View full text Add to dashboard Cite

show abstract

“…% of silver nanoparticles manifested considerable response to both E.coli and S.aureus. 108 The degradation studies were carried out in phosphate buffer of pH 7.4 for two weeks, and it was observed that the mechanical strength and elongation at break of the fibers was decreased by 12 % and 93 % respectively within three days. The samples became fragile after seven days of incubation.…”

Section: Biodegradation Characteristics Of Pga and Its Blendsmentioning

confidence: 99%

Poly(glycolic acid) (PGA): a versatile building block expanding high performance and sustainable bioplastic applications

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Polyglycolic acid (PGA) is a thermoplastic material with a high melting point and glass transition temperature, and it is more acidic and hydrophilic than PLA [99]. In addition, it is used as a surgical suture fiber because of its high mechanical strength and biocompatibility [100]. In the field of tissue engineering, solvent casting and compression molding are used to create PGA-based porous scaffolds [56].…”

Section: Polyglycolic Acidmentioning

confidence: 99%

3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs

et al. 2020

View full text Add to dashboard Cite

It is difficult to fabricate tubular-shaped tissues and organs (e.g., trachea, blood vessel, and esophagus tissue) with traditional biofabrication techniques (e.g., electrospinning, cell-sheet engineering, and mold-casting) because these have complicated multiple processes. In addition, the tubular-shaped tissues and organs have their own design with target-specific mechanical and biological properties. Therefore, the customized geometrical and physiological environment is required as one of the most critical factors for functional tissue regeneration. 3D bioprinting technology has been receiving attention for the fabrication of patient-tailored and complex-shaped free-form architecture with high reproducibility and versatility. Printable biocomposite inks that can facilitate to build tissue constructs with polymeric frameworks and biochemical microenvironmental cues are also being actively developed for the reconstruction of functional tissue. In this review, we delineated the state-of-the-art of 3D bioprinting techniques specifically for tubular tissue and organ regeneration. In addition, this review described biocomposite inks, such as natural and synthetic polymers. Several described engineering approaches using 3D bioprinting techniques and biocomposite inks may offer beneficial characteristics for the physiological mimicry of human tubular tissues and organs.

show abstract

Investigation on the Biodegradability and Antibacterial Properties of Nanohybrid Suture Based on Silver Incorporated PGA-PLGA Nanofibers

Cited by 21 publications

References 36 publications

Electrospun poly(e‐caprolactone)/propolis fiber morphology: A process optimisation study

Electrospun poly(e‐caprolactone)/propolis fiber morphology: A process optimisation study

Poly(glycolic acid) (PGA): a versatile building block expanding high performance and sustainable bioplastic applications

3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs

Contact Info

Product

Resources

About