High-speed backplane connectors are extensively used in digital baseband communication circuits. Connector degradation may lead to deterioration of the integrity of digital signals and is one of the major causes of low communication quality. In this study, an accelerated test was used to produce degraded connector samples. Based on the degradation characteristics of the connector electrical contact surface, the differential transmission method was applied to enhance signal integrity in such degraded electrical contact circuits. Referring to the Gigabit Ethernet standard, the differential signal waveforms and eye diagrams of high-speed channels with un-degraded and degraded connectors were studied. Improvement of the circuit reliability by differential transmission was demonstrated from the perspectives of both experimental investigations and analysis using probability calculations.