2003
DOI: 10.1255/jnirs.351
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Investigation on Deep Layer Measurements in the Cerebral Cortex within the Adult Head by near Infrared Spectroscopy Using an Absorbance Difference Technique

Abstract: Recent reports on modeled simulation of near infrared photons' paths in the adult head have shown that the cerebrospinal fluid functions as an optical guide, suggesting that non-invasive haemodynamic measurement of the deep layer of the cerebral cortex is difficult. Thus, the authors investigated the volume of the cortex measured by near infrared spectroscopy with the absorbance difference technique. This technique uses two radiation detector probes to yield short and long photon paths in order to realise sele… Show more

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Cited by 9 publications
(3 citation statements)
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References 14 publications
(27 reference statements)
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“…While light emitted by the Diagnodent pen has a wavelength of 655 nm, DRS uses a broader range of wavelengths (400-1600 nm), which should allow for deeper penetration through hard dental tissues. However, the penetration depth also depends on the distance between the optical fibers-the larger the distance, the higher the detection depth [58][59][60]. In this study, the distance between the optical fibers was 0.85 mm, which seems to be suitable for the detection of demineralization within the enamel, as DRS outperformed the Diagnodent pen and visual inspection in D1 and D2 lesions.…”
Section: Discussionmentioning
confidence: 64%
“…While light emitted by the Diagnodent pen has a wavelength of 655 nm, DRS uses a broader range of wavelengths (400-1600 nm), which should allow for deeper penetration through hard dental tissues. However, the penetration depth also depends on the distance between the optical fibers-the larger the distance, the higher the detection depth [58][59][60]. In this study, the distance between the optical fibers was 0.85 mm, which seems to be suitable for the detection of demineralization within the enamel, as DRS outperformed the Diagnodent pen and visual inspection in D1 and D2 lesions.…”
Section: Discussionmentioning
confidence: 64%
“…Spatially resolved spectroscopy (SRS) acquires the reflectance from objects at different spatial distances between the illumination and detectors, and it enables the obtaining of information from the sample at different depths as the transport path of photons generally forms a "banana-shape" in the tissue of the biological materials [28]. There are various configurations for SRS, including single-fiber-based, multi-fiber-based, and hyperspectral imaging-based, for measuring the optical absorption and scattering properties of food products [29][30][31].…”
Section: Introductionmentioning
confidence: 99%
“…Spatially-resolved spectroscopy is an emerging spectroscopic technique for measuring reflectance from the sample at different spatial distances between a point light source and detectors. Spatially-resolved (SR) spectra contain information about the sample at different layers (or depths) since the transport path of photons generally forms a “banana-shape” in biological tissues [ 20 ], shown in Figure 1 . Short spatial distances between the illumination and detectors would provide top layer information of the sample, while large source-detector distances is useful to obtain deep layer information of the sample [ 21 ].…”
Section: Introductionmentioning
confidence: 99%