Investigation of YAG:Ce-Based Optical Fibre Sensor for Use in Ultra-Fast External Beam Radiotherapy Dosimetry

Chen, Lingxia; O'Keeffe, Sinéad; Chen, Shuilin; Woulfe, Peter; Gillespie, Sean; Jiang, Benxue; Lewis, Elfed

doi:10.1109/jlt.2019.2919605

Cited by 20 publications

(7 citation statements)

References 22 publications

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“…A persistent challenge with LuAG:Ce SSCF lies in the self-absorption effect of Ce 3+ ions, which can result in significant scintillation light attenuation along the transmission process . In many existing radiation dose detectors, a short scintillator segment is often coupled with a transmission fiber such as the quartz optical fiber or plastic scintillating fibers − to address this issue. The role of the transmission fiber is to collect the scintillation signal from the scintillator, allowing for radiation signal detection.…”

Section: Introductionmentioning

confidence: 99%

A Couple-Free Structured LuAG:Ce-LuAG Scintillating Single Crystal Fiber Grown by a Laser-Heated Pedestal Growth Method

Wang,

Li,

Deng

et al. 2024

Crystal Growth & Design

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LuAG:Ce scintillators with excellent physical and scintillation properties have been widely utilized in radiation detection. However, three existing problems, such as Ce 3+ ions' selfabsorption effect, coupling-loss, and systems' radiation resistance, limit the LuAG:Ce scintillators' application. A couple-free LuAG:Ce-LuAG scintillating single crystal fiber (SSCF) for detection and transmission integrated performance was grown by the laser-heated pedestal growth method to address these. The Ce element along the growth direction of the as-grown LuAG:Ce-LuAG SSCF exhibits a three-segment distribution. The 1−1.5 cm length of LuAG:Ce detection segment for LuAG:Ce-LuAG SSCF is beneficial for enhancing the intensity of the output scintillation light at the collected end-face of the SSCF under X-ray or gammaray radiation. The thermal luminescence integrated intensity of LuAG:Ce SSCF still maintained 81% at 498 K and increased by 134% at 78 K compared to at room temperature. This design holds promise for the scintillation light strength collected from the transmission output end of the SSCF.

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Section: Introductionmentioning

confidence: 99%

A Couple-Free Structured LuAG:Ce-LuAG Scintillating Single Crystal Fiber Grown by a Laser-Heated Pedestal Growth Method

Wang,

Li,

Deng

et al. 2024

Crystal Growth & Design

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“…It is pertinent to probe the pulse structure of the photon beam for the PRDR dose rates to better understand the relationship between the instantaneous dose rate and the mean dose rate.Plastic scintillator detectors (PSD) are suitable for the measurement of pulse repetition frequency (PRF), pulse with, and pulse height due to their prompt light emission and short fluorescence decay time. 14 Radiochromic films, such as EBT3 film or EBT4 film, are suitable candidates for PRDR dosimetry due to their energy independence, angular independence, high spatial resolution, and 2D readout. [15][16][17] Several investigations have previously evaluated the dose rate dependence of radiochromic films for conventional dose rates above 100 MU/min.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dose‐rate dependence and IMRT QA suitability of EBT3 radiochromic films for pulse reduced dose‐rate radiotherapy (PRDR) dosimetry

Khan,

Radtke,

Hammer

et al. 2023

J Applied Clin Med Phys

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BackgroundPulsed reduced dose rate (PRDR) is an emerging radiotherapy technique for recurrent diseases. It is pertinent that the linac beam characteristics are evaluated for PRDR dose rates and a suitable dosimeter is employed for IMRT QA.PurposeThis study sought to investigate the pulse characteristics of a 6 MV photon beam during PRDR irradiations on a commercial linac. The feasibility of using EBT3 radiochromic film for use in IMRT QA was also investigated by comparing its response to a commercial diode array phantom.MethodsA plastic scintillator detector was employed to measure the photon pulse characteristics across nominal repetition rates (NRRs) in the 5–600 MU/min range. Film was irradiated with dose rates in the 0.033–4 Gy/min range to study the dose rate dependence. Five clinical PRDR treatment plans were selected for IMRT QA with the Delta4 phantom and EBT3 film sheets. The planned and measured dose were compared using gamma analysis with a criterion of 3%/3 mm. EBT3 film QA was performed using a cumulative technique and a weighting factor technique.ResultsNegligible differences were observed in the pulse width and height data between the investigated NRRs. The pulse width was measured to be 3.15 ± 0.01 and the PRF was calculated to be 3–357 Hz for the 5–600 MU/min NRRs. The EBT3 film was found to be dose rate independent within 3%. The gamma pass rates (GPRs) were above 99% and 90% for the Delta4 phantom and the EBT3 film using the cumulative QA method, respectively. GPRs as low as 80% were noted for the weighting factor EBT3 QA method.ConclusionsAltering the NRRs changes the mean dose rate while the instantaneous dose rate remains constant. The EBT3 film was found to be suitable for PRDR dosimetry and IMRT QA with minimal dose rate dependence.

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“…In previous developments using Ge-doped silica optical ber and an Elekta Synergy linear accelerator (powered by a magnetron source), characterization was carried out operating with a 6 MV beam energy for clinical X-ray conditions 23 . Herein, results are reported for an investigation using the same linac source operating in the electron beam mode, as popularly utilised in FLASH studies, focusing on timeresolved capabilities of the scintillator 24 . RL responses were recorded for six dose rates between 50 cGy/min and 600 cGy/min with corresponding PRF of 25 to 400 Hz.…”

Section: Introductionmentioning

confidence: 99%

The high dose rate sensing potential of a radiotherapy optical fiber dosimeter

Basaif¹,

Oresegun²,

Tarif³

et al. 2023

Preprint

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A perceived need exists for real-time dosimeters offering pulse-by-pulse temporal resolution to validate the delivery of the prescribed dose from clinical electron linear accelerators (linacs). In the case of linacs working at conventional (100–600 cGy/min) dose rates and operating in the bremsstrahlung mode, radioluminescence-emitting Ge-doped silica optical fibers have been shown to satisfy such demand. Ge-doped silica optical fiber scintillators measurements are made for a linac operating in the electron mode, delivering at dose rates up to 600 cGy/min. The radioluminescence response of the material as a function of dose has been measured using a Photomultiplier Tube (PMT) with a photon-counting circuit capable of 1-200 µs gating time, demonstrating dose linearity (R2 = 0.99971). Time-resolved radiation dosimetry measurements for a wide range of electron beam energies (6, 9, 12, 15 and 18 MeV) are reported. Measurements using a Multi Pixel Photon Counter (MPPC) connected to an oscilloscope shows the absence of saturation in the time resolved signal, freedom from performance limitations of residual memory or afterglow effects. Individual pulses at different energies have been analysed in terms of rise- and decay-times. While obtaining a qualitative assessment of the variation in pulse sub-structure, the variations likely arising from internal pulse manipulation for handling linac power delivery. The results point not only to the use of Ge-doped optical fiber scintillator in time-resolved dosimetry at conventional dose rates but also potential for use at the greater dose-rates of FLASH radiotherapy.

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Investigation of YAG:Ce-Based Optical Fibre Sensor for Use in Ultra-Fast External Beam Radiotherapy Dosimetry

Cited by 20 publications

References 22 publications

A Couple-Free Structured LuAG:Ce-LuAG Scintillating Single Crystal Fiber Grown by a Laser-Heated Pedestal Growth Method

A Couple-Free Structured LuAG:Ce-LuAG Scintillating Single Crystal Fiber Grown by a Laser-Heated Pedestal Growth Method

Dose‐rate dependence and IMRT QA suitability of EBT3 radiochromic films for pulse reduced dose‐rate radiotherapy (PRDR) dosimetry

The high dose rate sensing potential of a radiotherapy optical fiber dosimeter

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