Investigation of the surface reactivity of a sol–gel derived glass in the ternary system SiO2–CaO–P2O5

Mami, M.; Lucas‐Girot, A.; Oudadesse, Hassane; Dorbez-Sridi, Rachida; Mezahi, Fatima-Zohra; Dietrich, Elodie

doi:10.1016/j.apsusc.2008.05.340

Cited by 104 publications

(76 citation statements)

References 37 publications

(55 reference statements)

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“…This fact confirms the hypothesis of a precipitation of calcium ions from glass with hydrogen carbonate ions when glass immersed in SBF (26) .…”

Section: X-ray Diffractionsupporting

confidence: 89%

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

2015

Egypt. J. Biophys. Biomed. Engng.

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N PRESENT study, Different bioactive glass samples are prepared based on the following general formula: [65%SiO 2 -(25-X) %CaO-10% P 2 O 5 -X%ZnO)]; Ca 2+ is gradually substituted with Zn 2+(percentages of X= 0, 2, 4, 6, 8 and 10 mol %) by a quick alkalimediated sol-gel method. Development of a calcium phosphate (CP) layer on their surfaces is studied by soaking them in a simulated body fluid (SBF) for different periods. The consequent formation of the CP layer is studied by means of appropriate techniques such as X-ray diffractometry (XRD), Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) with an energy dispersive system (EDXS). The concentration of Ca 2+, P 5+ ions released from the samples into the SBF is measured by using UV-Vis Spectrophotometer and biochemical Kits. The results show that the formation of calcium phosphate layer on glass surfaces is inhibited by ZnO substitution, and strongly dependent on Zn 2+ concentration.Since the discovery of the first bioglass by Hench et al.. several other glass compositions have been imposed to improve the rehabilitation process in surgical applications. One of the important trends in recent studies is incorporation of some ions in the bioglass composition to improve its biofunctionallity. Regarding the stimulatory effects of some cations such as Mg 2+ , Sr 2+ and Zn 2+ on bone formation either by oral administration or local delivering process (2) , the effect of incorporation of these ions on the physical and physicochemical properties of sol-gel derived glasses has been reported. Zinc (Zn) is the second most prevalent trace element in the human body and is reported to stimulate fracture healing of bone (3) , reduces postmenopausal bone loss (4) , improves bone mineralization (5) , and improves skeletal strength (6) . Furthermore, Zn is an effective agent in killing bacterial strains commonly associated with infection in orthopedic surgeries (7) .Despite the numerous works reporting the stimulating effects of zinc, there are also studies that show other effects of zinc ions on bone cells. Popp et al. studied the effect of Zn 2+ -supplemented osteogenic medium on osteoblastic I

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“…This fact confirms the hypothesis of a precipitation of calcium ions from glass with hydrogen carbonate ions when glass immersed in SBF (26) .…”

Section: X-ray Diffractionsupporting

confidence: 89%

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

2015

Egypt. J. Biophys. Biomed. Engng.

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“…1. Figure 1a shows that the FTIR spectrum of CDESM prepared at 400°C contains peaks at 3367 cm −1 (N-H bonds or C-O asymmetric stretching), 2919 cm −1 (C-H bonds in = C-H and = CH 2 groups), 1760 cm −1 (C=O stretching vibration in carboxylic groups), 1650 cm −1 (amide C=O stretching), 1431 cm −1 (CaO, C=C) and 712 cm −1 ( 2 3 CO − of calcite) (Mami et al, 2008;Baláž et al, 2016;Tan et al, 2015;Botomé et al, 2017;Zaki et al, 2006;Tsai et al, 2006). It contains features that can be attributed to amines, amides, CaCO 3 , = C-H and =CH 2 , which remained in CDESM after preparation at 400°C.…”

Section: Ftir Analysismentioning

confidence: 99%

Characterization of Activated Carbon from Eggshell Membranes Prepared Using Sodium Acetate and Zinc Metal Activation

Mopoung¹,

Jitchaijaroenkul²

2017

American Journal of Applied Sciences

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The eggshell membranes of ducks and hens were carbonized or activated with 4 wt% sodium acetate or zinc at 400-600°C. The carbonized or activated products were characterized by SEM-EDS, TEM, FTIR and XRD. It was found that the suitable activation temperature for eggshell membranes is 500°C with 30.03-35.26% yield. The activation performance of CH 3 COONa for eggshell membrane activated carbon production was higher than that of Zn metal. The CO 3 2-, Ca-O, C=C, Na-O and C-O functional groups have been formed on the surface of eggshell membrane activated carbon materials during both CH 3 COONa and Zn activation. Furthermore, CaO, MgO, Na 2 O and ZnO have also accumulated on eggshell membrane activated carbon materials with high content and regular dispersion. It was shown that the particles on the duck eggshell membrane activated carbon formed with Zn had weaker attachment on the surface than for duck eggshell membrane activated carbon formed with CH 3 COONa at same temperature. The XRD and TEM results revealed that the eggshell membrane activated carbons consist of an amorphous carbon matrix with some disordered graphite carbon matrix, spherical particles and nanofiber.

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“…In the group of silicate bioactive glasses, those obtained using sol-gel method exhibit much higher surface area and the presence of siloxane groups (Si-OH) in their structure. Thus, their bioactivity and cellular response are usually enhanced compared to conventional meltderived glasses [14]. Therefore, the combination of PCL matrix with gel-derived bioactive glass fillers creates possibility of not only modulating material degradation rate but also imparting osteoinductive and bioactive properties.…”

Section: Introductionmentioning

confidence: 99%

A new insight into in vitro behaviour of poly(ε-caprolactone)/bioactive glass composites in biologically related fluids

et al. 2017

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In the present work, the role of content, size and chemical composition of gel-derived bioactive glass particles from the SiO 2 -CaO-P 2 O 5 system in modulating the in vitro bioactivity, osteoinductive properties and long-term (up to 15 months) degradation behaviour of poly(e-caprolactone)-based composite films was investigated. Bioactivity was assessed in simulated body fluid (SBF) and HEPES-free Dulbecco's modified Eagle medium (DMEM) supplemented with 10% foetal bovine serum (FBS), while hydrolytic degradation tests were performed in phosphate buffer saline. Obtained composite films showed excellent calcium phosphate (CaP) layer forming ability in both SBF and DMEM-10% FBS. However, kinetics of bioactivity process strongly depended on the type of medium used. The layer of amino acids and proteins, derived from cell culture medium, on the surfaces of composites created barrier that inhibited release of the ions on the one hand, while increasing nucleation density of calcium phosphates, affecting the morphology of formed CaP layers on the other. The presence of bioactive glass fillers was shown to impart osteoinductive properties to obtained films, supporting osteoblast attachment and proliferation, as well as stimulating cell differentiation and also matrix mineralization process in vitro. We showed that kinetics of bioactivity process and also osteoinductive properties of composite films could be easily modulated with the use of different contents and chemical compositions of fillers. The results showed that modification of PCL matrix with bioactive glass particles accelerated its degradation. We proved that the degradation rate of composites could be controlled and optimized for bone regeneration, in particular by using bioactive fillers causing different calcium phosphate layer forming ability on the surfaces of composites, depending on particle size and chemical composition. We have presented new opportunities to design and obtain multifunctional composites with tunable degradation and bioactivity kinetics, as well as biological properties that can meet complex requirements of bone tissue engineering.

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Investigation of the surface reactivity of a sol–gel derived glass in the ternary system SiO2–CaO–P2O5

Cited by 104 publications

References 37 publications

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

Characterization of Activated Carbon from Eggshell Membranes Prepared Using Sodium Acetate and Zinc Metal Activation

A new insight into in vitro behaviour of poly(ε-caprolactone)/bioactive glass composites in biologically related fluids

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