Investigation of the risk factors associated with osteoporosis in postmenopausal women

Poçan, Ahmet Gürhan; Sönmezer, Meltem; Topal, Kenan; Aslan, Batuhan; Gereklioğlu, Çiğdem; Sönmezer, Murat

doi:10.4274/jtgga.galenos.2023.2023-7-9

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…Several studies have evaluated the risk of osteoporosis in postmenopausal women aged 45 years and older and the positive association between osteoporosis and age >45 years [12][13][14]. In one study, osteoporosis was found in 12% of women aged 40-49 years, 21.8% of women aged 50-59 years, and 45.7% of women aged >60 years [12].…”

Section: Discussionmentioning

confidence: 99%

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The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

Madiyeva,

Rymbaeva,

Kaskabayeva

et al. 2024

Preprint

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Osteoporosis is considered a serious public health problem, particularly affecting the postmenopausal period. In 2018, in the Republic of Kazakhstan the total and primary incidence was 10 and 3.7 cases per 100,000 adults, respectively. The objective is to study osteoporosis prevalence and indicate main factors affecting low bone mineral density by screening adult population of Abay region, Kazakhstan. The target group were 641 respondents aged between 18 and 65 years old, Kazakh population living in Abay region since birth. All participants filled out questionnaire and had a bone mineral density measurement by dual energy X-ray absorptiometry (DXA) between July 15, 2023 and February 29, 2024. Logistic regression analysis was conducted to assess the association between low bone mineral density and key demographic characteristics, aforementioned lifestyle factors and nutrition habits. We identified the prevalence of low bone density and osteoporosis at the level of 34.1% with the highest prevalence in the older population group (50+ years) - 48.3%. Regression analysis revealed a number of indicators associated with the likelihood of bone sparing. However, only 4 of these showed significance in the final multivariate model (R2=22.4%). These included age (AOR 1.05), body mass index (AOR 0.92), fracture history (AOR 1.64), consumption of nuts and dried fruits were associated with lower prevalence of osteoporosis (AOR 0.48). Our study was the first in Kazakhstan that investigates the association of key demographic, behavior and anamnestic factors with low mineral density.

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Section: Discussionmentioning

confidence: 99%

“…In another observational study, the prevalence of osteoporosis was significantly lower in those aged 40-50 years than in those aged 50 years and older, by a factor of about 20-40 [13]. The mean age of women was 59.5±8.6 years, and the mean age of menopause onset was 49.0±3.4 years [14].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

Madiyeva,

Rymbaeva,

Kaskabayeva

et al. 2024

Preprint

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“…When measuring the lumbar spine (LS) in Turkish women [ 21 ], the incidences of normal BMD (31.4%), osteopenia (48.2%), and osteoporosis (20.5%) were higher than those found in another study by the Turkish researchers İpek A et al [ 18 ]. In a study by Thambiah SC et al [ 22 ], the prevalence of osteoporosis in the LS in Thai women in the age range of 55–59 years was 22.6%.…”

Section: Discussionmentioning

confidence: 99%

The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

Madiyeva,

Rymbayeva,

Kaskabayeva

et al. 2024

IJERPH

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Osteoporosis is considered a serious public health problem that particularly affects the postmenopausal period. In 2018, in the Republic of Kazakhstan, the prevalence of osteoporosis was 10.0, and the incidence was 3.7 new cases, per 100,000 adults, respectively. The objective of this study was to assess the prevalence of osteoporosis and indicate the main factors affecting low bone mineral density by screening the adult population of the Abay region, Kazakhstan. The target group comprised 641 respondents aged between 18 and 65 years old, from a Kazakh population, who had been living in the Abay region since birth. All participants filled out a questionnaire and were subjected to a bone mineral density measurement by means of dual-energy X-ray absorptiometry (DXA) between 15 July 2023 and 29 February 2024. Logistic regression analysis was conducted to assess the association between low bone mineral density and key demographic characteristics, such as lifestyle factors and nutritional habits. We identified the prevalence of low bone mass (osteopenia) and osteoporosis to be 34.1%, with the highest prevalence of 48.3% being found in the older population group (50+ years). The regression analysis revealed a number of indicators associated with the likelihood of bone sparing. However, only four of these showed significance in the final multivariate model (R2 = 22.4%). These were age (adjusted odds ratio (AOR) 1.05) and fracture history (AOR 1.64) directly associated with the likelihood of low bone density. Meanwhile, the body mass index (AOR 0.92) and the consumption of nuts and dried fruits (AOR 0.48) reduced the chance of bone tissue demineralization. Additional studies examining the prevalence and any emerging risk factors for osteoporosis are needed to advance clinical epidemiological knowledge and implement public health programs.

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Prevalence and Risk Factors of Osteoporosis: a Cross-Sectional Study in a Tertiary Center

Ozmen,

Kurt,

Timur

et al. 2024

Preprint

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Background: Osteoporosis is a common disease of the skeletal system that increases the risk of fracture. The prevalence of osteoporosis has been increasing as the aging population increases, affecting more than 200 million people worldwide. This study aimed to shed light on the clinical impact of osteoporosis on women’s health and quality of life by evaluating the prevalence and risk factors for this disease among postmenopausal women, using a 10-year dataset from a tertiary center. Materials and Methods: This retrospective cohort study was conducted at Dokuz Eylul University, Department of Obstetrics and Gynecology, between 2010 and 2022. A total of 3289 postmenopausal women aged 50-60 years who were undergoing routine gynecological checkups were included in the study. Patients with a prior diagnosis, a history of medical conditions or who were taking medications affecting bone mineral density were excluded. Data on demographics, smoking status, diabetes status, body-mass index (BMI), parity, and fracture history were collected. Bone mineral density sores were classified as normal, osteopenia, or osteoporosis. Results: The prevalence of osteoporosis was 10.4%. The median age of the patients was 56.0 years. Smoking, diabetes, and a history of bone fractures were found to significantly increase the risk of osteoporosis. BMI was found to have a protective effect against osteoporosis. According to multivariate analysis, the risk of osteoporosis increased by 2.46 times in patients who smoke, 3.78 times in patients with diabetes, and 6.23 times in patients with a history of fractures. Conclusions:Awareness of modifiable risk factors such as smoking is crucial for preventing osteoporosis-related complications. Diabetes, even when it is not complicated, increases the risk of osteoporosis. Physical exercise, calcium, and vitamin D intake are important, especially during young adulthood, as they are the primary contributors to peak bone mass. Because ne fractures are more common in patients with osteopenia, early diagnosis and routine screening can mitigate future complications.

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Investigation of the risk factors associated with osteoporosis in postmenopausal women

Cited by 3 publications

References 16 publications

The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

The Prevalence and Risk Factors of Low Bone Mineral Density in the Population of the Abay Region of Kazakhstan

Prevalence and Risk Factors of Osteoporosis: a Cross-Sectional Study in a Tertiary Center

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