Investigation of the properties of chitosan–Pluronic based nanogel drug delivery systems utilizing various Pluronic types
Van Toan Nguyen,
Dinh Trung Nguyen,
Dang Nam Nguyen
et al.
Abstract:This research aimed to create self‐assembled nanogel particles using chitosan grafted with various types of Pluronic to encapsulate curcumin, a hydrophobic biological agent. The study explored the properties of CS–Pluronic nanogels using Pluronic types L61, P123, F127, and F68, each varying in hydrophilic–lipophilic balance (HLB) index. Findings indicated that the critical micelle concentration (CMC) of Pluronics and CS–Pluronic copolymers did not depend on the HLB values but were influenced by the structural … Show more
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