Investigation of the phenylation of methyl-quinolines using tritium-labeled nucleogenic phenyl cations

Quinolinium Structure as Labeled Biomarkers

“…Unfortunately synthesis of such derivatives is very difficult and complex due to the lack of direct phenylation of nitrogen atom [21] [22]. Our elaborated nuclear-chemical synthetic method us-ing free nucleogenic phenyl cations generated by tritium β-decay allows the one-step synthesis of hardly available N-phenyl-substituted heterocyclic compounds [23]- [27].…”