Investigation of the optimal detector arrangement for the helmet-chin PET – A simulation study

Ahmed, Abdella; Tashima, Hideaki; Yoshida, Eiji; Yamaya, Taiga

doi:10.1016/j.nima.2017.03.044

Cited by 10 publications

(13 citation statements)

References 12 publications

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“…It is evident that the more the layers, the better resolution the system achieves. When the DOI resolution is designed to be 6.67 mm, the best spatial resolution of our dedicated brain system is achieved near the center of the FOV, which is 1.98 mm, better than the helmet‐chin system (2.5 mm with DOI resolution being 5 mm) and the HRRT system (2.5 mm with DOI resolution being 10 mm) . We then chose DOI resolution of 6.67 mm for simulations in the rest of this work.…”

Section: Resultsmentioning

confidence: 99%

“…Gong et al simulated a helmet structure system that consists of six side rings with different diameters, a top panel, and a bottom panel. A slightly different helmet PET was first presented and then upgraded to the helmet‐chin system . The scanner enhances the imaging performance for both bottom and top region of the brain.…”

Section: Introductionmentioning

confidence: 99%

“…A slightly different helmet PET was first presented and then upgraded to the helmet-chin system. [14][15][16][17] The scanner enhances the imaging performance for both bottom and top region of the brain. Moghaddam et al 18 designed a spherical brain PET system with liquid xenon detectors, with a large solid angle 19 but much complexity in realization in practice.…”

Section: Introductionmentioning

confidence: 99%

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Simulation study of a high‐performance brain PET system with dodecahedral geometry

et al. 2018

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Simulation study of a high‐performance brain PET system with dodecahedral geometry

et al. 2018

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“…All the MCE’s are tilted with their main axes pointing towards the center of the FOV in a “spherical arrangement” previously introduced by Ahmed et al . in [ 27 ] which provides a larger solid angle and, therefore, a better geometrical efficiency than a “multi-ring arrangement”. It is worth to mention that, in case of a PET system such as in [ 27 ], the geometric efficiency may increase with the square of the solid angular coverage since a valid event requires the detection of both coincident annihilation photons.…”

Section: Methodsmentioning

confidence: 99%

“…We have carried out a series of simulation studies to evaluate the use of the SCE gamma camera design with a spherical arrangement [ 27 ], and to compare the imaging properties offered by the non-conventional apertures with the ones offered by traditional loftholes [ 28 ]. The results show that the combination of the SCE camera design and the non-conventional micro-slit and micro-ring apertures would allow for an excellent spatial resolution and high sensitivity over a clinically relevant FOV.…”

Section: Introductionmentioning

confidence: 99%

Design Study of an Ultrahigh Resolution Brain SPECT System Using a Synthetic Compound-Eye Camera Design With Micro-Slit and Micro-Ring Apertures

Zannoni

Yang

Meng

2021

IEEE Trans. Med. Imaging

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In this paper, we discuss the design study for a brain SPECT imaging system, referred to as the HelmetSPECT system, based on a spherical synthetic compound-eye (SCE) gamma camera design. The design utilizes a large number ( ~500) of semiconductor detector modules, each coupled to an aperture with a very narrow opening for high-resolution SPECT imaging applications. In this study, we demonstrate that this novel system design could provide an excellent spatial resolution, a very high sensitivity, and a rich angular sampling without scanning motion over a clinically relevant field-of-view (FOV). These properties make the proposed HelmetSPECT system attractive for dynamic imaging of epileptic patients during seizures. In ictal SPECT, there is typically no prior information on where the seizures would happen, and both the imaging resolution and quantitative accuracy of the dynamic SPECT images would provide critical information for staging the seizures outbreak and refining the plans for subsequent surgical intervention.We report the performance evaluation and comparison among similar system geometries using non-conventional apertures, such as micro-ring and micro-slit, and traditional lofthole apertures. We demonstrate that the combination of ultrahigh-resolution imaging detectors, the SCE gamma camera design, and the micro-ring and micro-slit apertures would offer an interesting approach for the future ultrahigh-resolution clinical SPECT imaging systems without sacrificing system sensitivity and FOV.

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First prototyping of a dedicated PET system with the hemisphere detector arrangement

et al. 2019

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A strong demand is expected for high-sensitivity, high-resolution and low-cost brain positron emission tomography (PET) imaging for early diagnosis of dementia, as well as for general neuroscience studies. Therefore, we have proposed novel geometries of a hemisphere detector arrangement for high-sensitivity brain imaging, in which an add-on detector at the chin position or neck position helps in sensitivity uniformity improvement. In this study, we developed the first prototype system for proof-of-concept using four-layer depth-of-interaction detectors, each of which consisted of 16 × 16 × 4 Zr-doped GSO crystals with dimensions of 2.8 × 2.8 × 7.5 mm3 and a high-sensitivity 64-channel flat-panel photomultiplier tube. We used 47 detectors to form a hemisphere detector with a hemisphere shape of 25 cm inner diameter and 50 cm outer diameter, and we used seven detectors for each of the add-on detectors. The total detector number of 54 was about one-fourth that of a typical whole-body PET scanner. The hemisphere detector for the prototype system was realized by multiple rings having different numbers of detectors and a cross-shaped top detector unit covering the top. Performance evaluation showed uniform spatial resolutions of 3–4 mm by the filtered back-projection method. Imaging tests of a hot-rod phantom done with an iterative method were able to resolve 2.2 mm rods. Peak sensitivity was measured as more than 10% at a region near the top of the head, which was achieved with the help of the top detector unit. In addition, using the prototype system, we performed the first FDG clinical test with a healthy volunteer. The results showed that the proposed geometries had high potential for realizing high-sensitivity, high-resolution, and low-cost brain PET imaging. As for the add-on detector position, it was shown that the neck position resulted in higher sensitivity and wider field of view (FOV) than the chin position because the add-on detector at the neck position can be placed continuously to the hemisphere detector and close to the FOV.

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Investigation of the optimal detector arrangement for the helmet-chin PET – A simulation study

Cited by 10 publications

References 12 publications

Simulation study of a high‐performance brain PET system with dodecahedral geometry

Simulation study of a high‐performance brain PET system with dodecahedral geometry

Design Study of an Ultrahigh Resolution Brain SPECT System Using a Synthetic Compound-Eye Camera Design With Micro-Slit and Micro-Ring Apertures

First prototyping of a dedicated PET system with the hemisphere detector arrangement

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