“…This latter finding suggests selection of enzyme ratios, erring on the low side of EGs, may effectively minimize enzyme costs while maintaining endo/exo synergism . The role of EGs in endo/exo synergism, in particular Tr Cel5A, continues to be a major research focus today. − As new approaches for describing cellulase kinetics become available, models describing endo/exo synergism re-emerge, challenging the way we think about processive cellulase action and the role EGs play …”