Investigation of the chemical composition of antibacterial Psidium guajava extract and partitions against foodborne pathogens

Hall, Audrey M.; Baskiyar, Swati; Heck, Kabre L.; Hayden, Michelle D.; Ren, Chang; Nguyen, Chris; Seals, Cheryl; Monu, Emefa; Calderón, Ángela I.

doi:10.1016/j.foodchem.2022.134400

Cited by 3 publications

(1 citation statement)

References 31 publications

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“…Sebanyak ± 5 g ekstrak yang telah diperoleh dipartisi menggunakan variasi pelarut [27] berupa pelarut n-heksana, etil asetat dan kloroform masing-masing sebanyak 10 mL. Proses partisi menggunakan corong pisah 50 mL.…”

Section: Partisi Esktrak Tanaman Araunclassified

PROFIL FITOKIMIA DAN ANALISIS TOKSISITAS Ficus racemosa L. MENGGUNAKAN METODE BRINE SHRIMP (Artemia salina) LETHALITY TEST

Suryani

2023

Alo

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A traditional plant, Ficus racemosa L., known as the ara plant in West Nusa Tenggara, is potentially beneficial as a drug candidate, which is one option to develop the biodiversity of natural ingredients in Indonesia. The extract was produced by maceration method with ethanol 96% solvent. Furthermore, they partitioned using various solvents, n-hexane, ethyl acetate, and chloroform. The presence or absence of secondary metabolite is determined by the phytochemical screening test. Meanwhile, the Brine Shrimp Lethality Test (BSLT) is a toxicity screening to determine the LC50 of extract and their partition with various concentrations used were 50, 100, 250, 500, and 1000 ppm. The metabolite secondary flavonoids, alkaloids, and saponins are confirmed. The analysis showed that LC50 of extract was 218,34 ppm; n-hexane fraction was 413,57 ppm; ethyl acetate fraction was 309.51 ppm; and chloroform fraction was 314.60 ppm; all had toxic potential.

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Section: Partisi Esktrak Tanaman Araunclassified

PROFIL FITOKIMIA DAN ANALISIS TOKSISITAS Ficus racemosa L. MENGGUNAKAN METODE BRINE SHRIMP (Artemia salina) LETHALITY TEST

Suryani

2023

Alo

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Psidium guajava L.- dichloromethane and ethyl acetate fractions ameliorate striped catfish (Pangasianodon hypophthalmus) status via immune response, inflammatory, and apoptosis pathways

Như

Bich

Thanh

et al. 2023

Fish & Shellfish Immunology

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Ethnobotany, phytochemistry, and biological activities of Psidium guajava in the treatment of diarrhea: a review

Liu,

Jullian,

Chassagne

2024

Front. Pharmacol.

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Psidium guajava: is a tropical tree that is widely used in traditional medicine, especially for treating diarrhea. While P. guajava has been the subject of numerous reviews, none have specifically examined its ethnobotany, pharmacology, and phytochemistry in relation to its antidiarrheal activity. This review aims to summarize the evidence of effectiveness and safety of P. guajava in the treatment of diarrhea. Literature searches were conducted through Web of Science, PubMed, and ScienceDirect by using keywords “Psidium guajava” and “diarrhea” in October 2022. A total of 189 studies were included in this review. P. guajava is widely used in traditional medicine in 44 countries. Decoction and oral were the most represented method of preparation and administration, respectively, while leaves represented the most frequently cited part of the plant. Around 27 antidiarrheal or antibacterial compounds have been isolated and identified, including benzophenone glycosides, terpenes, polysaccharides, phenols, and flavonoids. This article presents ethnobotanical and pharmacological evidence for the efficacy of P. guajava leaves in the treatment of diarrhea and provides reference information for further investigation of this plant. However, despite the large number of publications on the topic, there are still some questions to answer: are quercetin and its glycosides the only ones to act as antidiarrheal agents? What is the mechanism of action of P. guajava antidiarrheal compounds? are the use of guava leaves safe in all types of populations including children, and at what dosage? To answer these questions, more complete phytochemical studies and systematic clinical trials are needed.

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Investigation of the chemical composition of antibacterial Psidium guajava extract and partitions against foodborne pathogens

Cited by 3 publications

References 31 publications

PROFIL FITOKIMIA DAN ANALISIS TOKSISITAS Ficus racemosa L. MENGGUNAKAN METODE BRINE SHRIMP (Artemia salina) LETHALITY TEST

PROFIL FITOKIMIA DAN ANALISIS TOKSISITAS Ficus racemosa L. MENGGUNAKAN METODE BRINE SHRIMP (Artemia salina) LETHALITY TEST

Psidium guajava L.- dichloromethane and ethyl acetate fractions ameliorate striped catfish (Pangasianodon hypophthalmus) status via immune response, inflammatory, and apoptosis pathways

Ethnobotany, phytochemistry, and biological activities of Psidium guajava in the treatment of diarrhea: a review

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