Investigation of the association between serum uric acid levels and HEART risk score in patients with acute coronary syndrome

Abstract

The association between uric acid (UA) and cardio‐metabolic conditions has been recognized for a long time. However, recently, a body of evidence has highlighted the independent role of UA in a series of conditions, including renal and cardiovascular diseases. In this light, data regarding the prognostic role of UA in acute coronary syndrome (ACS) is scarce. A total number of 100 patients, 59 males and 41 females, diagnosed with ACS were recruited in this study. At the time of admission to the hospital, the serum level of UA was measured. In addition, the HEART score was calculated based on each patients' profile. Participants were on average 61.37 ± 12.08 years old. The most prevalent risk factors were hypertension (48%), a history of coronary artery disease (40%), and diabetes mellitus (33%). The average serum level of UA was 5.81 ± 1.81 mg/dl, and the calculated HEART score had a median of six (minimum of two and maximum of ten). A positive yet statistically insignificant correlation was found between the measured UA level and the calculated HEART score (R = 0.375, p = 0.090). However, further studies with larger sample size are required to assess the direct association of UA level with major adverse cardiac events in patients with cardiovascular disease.

Evaluation of long‐term outcomes of percutaneous coronary intervention in patients with moderate to severe calcified coronary artery lesions

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Impact of Hyperuricemia and Urate-Lowering Agents on Cardiovascular Diseases

“…Khameneh Bagheri et al 59 conducted a study involving 100 patients diagnosed with ACS, including 59 males and 41 females. The serum level of UA was measured at the time of hospital admission, and the patients’ profiles were used to calculate the HEART score, with the average score being 6, with a range of 2 to 10.…”

“…The average serum level of uric acid was 5.81 ± 1.81 mg/dl, The study found a positive correlation between the measured UA level and the calculated HEART score, but the correlation did not reach statistical significance ( R = 0.375, P = 0.090). 59 …”

Diyabetli Hastalarda Miyokard Perfüzyon Sintigrafisinde Miyokard İskemisini Öngörmede Ürik Asit-HDL Kolesterol Oranının Rolü

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